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How to get fromGrenoble to Mainzby train, plane, train (TGV), bus, car, or train (Trenitalia)

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There are 9 ways to get from Grenoble to Mainz by train, plane, train (TGV), bus, car, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Lyon–Saint Exupéry Airport, fly to Frankfurt

    best
    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane plane LYS - FRA
    5h 2m
    €136–370

  2. Bus

    cheapest
    1. Take the bus from Grenoble to Lyonbus bus S1777 / ...
    2. Take the bus from Lyon - Gerland Bus Station to Frankfurt - Airport Bus Stationbus bus BlaBlaCar Bus
    14h 52m
    €68–131

  3. Train

    1. Take the train from Grenoble to Lyon Part Dieutrain train Ter
    2. Take the train from Lyon Part Dieu to Mannheim Hbftrain train Tgv
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    9h 17m
    €165–309

  4. Drive  717.2 km

    1. Drive from Grenoble to Mainzcar car 717.2 km
    6h 33m
    €115–166

  5. Train to Geneva International Airport, fly to Frankfurt

    1. Take the train from Grenoble to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane plane GVA - FRA
    6h 29m
    €148–340

  6. Train to Marseille Provence Airport, fly to Frankfurt

    1. Take the train from Grenoble to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Frankfurt (FRA)plane plane MRS - FRA
    6h 36m
    €157–368

  7. Train to Lyon–Saint Exupéry Airport, fly to Strasbourg International Airport, train

    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane plane LYS - SXB
    3. Take the train from Strasbourg Bahnhof to Mannheim, Hauptbahnhoftrain train
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train
    7h 19m
    €157–482

  8. Train via Basel

    1. Take the train from Grenoble to Genevetrain train Ter
    2. Take the train from Genève to Renens VDtrain train Ic1 / ...
    3. Take the train from Renens VD to Basel SBBtrain train
    4. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    10h 18m
    €159–349

  9. Bus via Freiburg im Breisgau

    1. Take the bus from Grenoble to Freiburgbus bus FlixBus N872
    2. Take the bus from Freiburg to Mainz central train stationbus bus FlixBus 476
    15h 46m
    €70–112

Grenoble to Mainz by train

Calendar7Weekly Trains
Duration9h 17mAverage Duration
Ticket€165Cheapest Price
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Comparing Your Travel Options

Map of how to get from Grenoble to Mainz.ExpandLaunch map view
  • Distance: 688.2 km
  • Duration: 5h 2m

What companies run services between Grenoble, France and Mainz, Germany?

You can take a train from Grenoble to Mainz, Hauptbahnhof via Lyon Part Dieu, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 9h 17m. Alternatively, you can take a bus from Grenoble to Mainz, Stadtpark via Lyon - Gerland Bus Station, Frankfurt - Airport Bus Station, Frankfurt, and Kelsterbach Rathaus in around 14h 52m.

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