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How to get fromGrenoble to Mainzby train, plane, train (TGV), bus, car, or train (Trenitalia)

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There are 8 ways to get from Grenoble to Mainz by train, plane, train (TGV), bus, car, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Lyon–Saint Exupéry Airport, fly to Frankfurt

    best
    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane plane LYS - FRA
    4h 59m
    €138–309

  2. Bus, train

    cheapest
    1. Take the bus from Grenoble to Freiburgbus bus
    2. Take the bus from Freiburg to Mannheim central bus stationbus bus
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    16h 41m
    €68–114

  3. Train via Paris

    1. Take the train from Grenoble to Paris Gare De Lyontrain train Tgv
    2. Take the train from Paris Est to Mannheim Hbftrain train Ice
    3. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    8h 49m
    €223–634

  4. Bus

    1. Take the bus from Grenoble - Bus Station to Frankfurt - Airport Bus Stationbus bus BlaBlaCar Bus
    14h 27m
    €70–119

  5. Drive  717.2 km

    1. Drive from Grenoble to Mainzcar car 717.2 km
    6h 33m
    €112–162

  6. Train to Geneva International Airport, fly to Frankfurt

    1. Take the train from Grenoble to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane plane GVA - FRA
    6h 30m
    €154–343

  7. Train to Lyon–Saint Exupéry Airport, fly to Strasbourg International Airport, train

    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Strasbourg International Airport (SXB)plane plane LYS - SXB
    3. Take the train from Strasbourg to Mannheim Hbftrain train
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train
    7h 9m
    €160–489

  8. Train

    1. Take the train from Grenoble to Genevetrain train Ter
    2. Take the train from Genève to Renens VDtrain train Ic1 / ...
    3. Take the train from Renens VD to Basel SBBtrain train
    4. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    10h 18m
    €165–498

Grenoble to Mainz by train and foot

Calendar92Weekly Services
Duration8h 49mAverage Duration
Ticket€223Cheapest Price
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Questions & Answers

Map of how to get from Grenoble to Mainz.ExpandLaunch map view
  • Distance: 688.2 km
  • Duration: 4h 59m

What companies run services between Grenoble, France and Mainz, Germany?

You can take a train from Grenoble to Mainz, Hauptbahnhof via Paris Gare de Lyon, Paris Nord, Paris Est, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 8h 49m. Alternatively, BlaBlaCar Bus operates a bus from Grenoble - Bus Station to Frankfurt - Airport Bus Station once daily. Tickets cost €65–120 and the journey takes 12h 45m.

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