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How to get fromGrenoble to Mendrisioby train (Trenitalia), bus, car, train, plane, or train (TGV)

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There are 6 ways to get from Grenoble to Mendrisio by train (Trenitalia), bus, car, train, plane, or train (TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Grenoble to Chambery Challes Les Eauxtrain train Ter
    2. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Mendrisiotrain train
    6h 45m
    CHF 65–161

  2. Bus

    cheapest
    1. Take the bus from Grenoble to Turinbus bus FlixBus N740 / ...
    2. Take the bus from Turin to Comobus bus FlixBus 456
    8h 59m
    CHF 31–64

  3. Drive 392.9 km

    1. Drive from Grenoble to Mendrisiocar car 392.9 km
    4h 20m
    CHF 65–93

  4. Train to Geneva International Airport, fly, train

    1. Take the train from Grenoble to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Milano Malpensa Airport (MXP)plane plane GVA - MXP
    3. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    7h 15m
    CHF 103–324

  5. Train via Milan

    1. Take the train from Grenoble to Chambery Challes Les Eauxtrain train Ter
    2. Take the train from Chambery Challes Les Eaux to Milano P.Garibalditrain train Tgv
    3. Take the train from Milano Centrale to Mendrisiotrain train
    7h 53m
    CHF 96–208

  6. Train to Lyon–Saint Exupéry Airport, fly, train

    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Milano Malpensa Airport (MXP)plane plane LYS - MXP
    3. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    5h 32m
    CHF 77–260

Grenoble to Mendrisio by train

Calendar28Weekly Trains
Duration6h 45mAverage Duration
TicketCHF 65Cheapest Price
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Questions & Answers

Map of how to get from Grenoble to Mendrisio.ExpandLaunch map view
  • Distance: 463.3 km
  • Duration: 6h 45m

What companies run services between Grenoble, France and Mendrisio, Switzerland?

You can take a train from Grenoble to Mendrisio via Chambery Challes Les Eaux and Milano Centrale in around 6h 45m. Alternatively, you can take a bus from Grenoble to Mendrisio, Autosilo via Turin, Como, Como - San Rocchetto, and Chiasso, Stazione in around 8h 59m.

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