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How to get fromGrenoble to Mendrisioby train (Trenitalia), bus, train, car, or plane

Find Transport to Mendrisio

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There are 6 ways to get from Grenoble to Mendrisio by train (Trenitalia), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Grenoble to Chambery Challes Les Eauxtrain train Ter
    2. Take the train from Chambery Challes Les Eaux to Milano Centraletrain train Fr
    3. Take the train from Milano Centrale to Mendrisiotrain train
    6h 42m
    CHF 63–104

  2. Bus

    cheapest
    1. Take the bus from Grenoble to Turinbus bus 740 / ...
    2. Take the bus from Turin to Milanbus bus 467 / ...
    3. Take the bus from Milan Malpensa Airport T1 to Como P.le S. Gottardobus bus
    8h 49m
    CHF 23–62

  3. Bus, train

    1. Take the bus from Grenoble to Turinbus bus 740 / ...
    2. Take the bus from Turin Porta Susa to Milan Malpensa Airport Arrivals Terminal 2bus bus
    3. Take the train from Malpensa Aeroporto T2 to Mendrisiotrain train S50
    7h 25m
    CHF 24–92

  4. Drive  392.9 km

    1. Drive from Grenoble to Mendrisiocar car 392.9 km
    4h 20m
    CHF 76–109

  5. Train to Lyon–Saint Exupéry Airport, fly, train

    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Milano Malpensa Airport (MXP)plane plane LYS - MXP
    3. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    5h 31m
    CHF 78–239

  6. Train to Geneva International Airport, fly, train

    1. Take the train from Grenoble to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Milano Malpensa Airport (MXP)plane plane GVA - MXP
    3. Take the train from Malpensa Aeroporto T1 to Mendrisiotrain train
    8h 45m
    CHF 99–267

Grenoble to Mendrisio by train

Calendar14Weekly Trains
Duration6h 42mAverage Duration
TicketCHF 63Cheapest Price
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Comparing Your Travel Options

Map of how to get from Grenoble to Mendrisio.ExpandLaunch map view
  • Distance: 463.3 km
  • Duration: 6h 42m

What companies run services between Grenoble, France and Mendrisio, Switzerland?

You can take a train from Grenoble to Mendrisio via Chambery Challes Les Eaux and Milano Centrale in around 6h 42m. Alternatively, you can take a bus from Grenoble to Mendrisio, Autosilo via Turin, Milan, Milan Malpensa Airport T1, Como P.le S. Gottardo, Como - San Rocchetto, and Chiasso, Stazione in around 8h 49m.

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