There are 10 ways to get from Grenoble to Palermo by train, plane, ferry, car, car ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Lyon–Saint Exupéry Airport, fly
best- Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain
- Fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO)plane LYS - PMO
5h 48m€81–293Train, train to Turin Caselle Airport, fly
cheapest- Take the train from Grenoble to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Palermo Airport (PMO)plane TRN - PMO
8h 36m€58–299Train, ferry
- Take the train from Grenoble to Chambery Challes Les Eauxtrain Ter
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
20h 16mDrive, car ferry
- Drive from Grenoble to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
24h 51m€162–239Bus
- Take the bus from Grenoble to Turinbus FlixBus N740 / ...
- Take the bus from Turin to Palermobus N597
29h€145–245Train to Geneva International Airport, fly
- Take the train from Grenoble to Genevetrain
- Fly from Geneva International Airport (GVA) to Palermo Airport (PMO)plane GVA - PMO
7h 24m€87–397Train, train to Marseille Provence Airport, fly
- Take the train from Grenoble to Valence Tgv Rhone-Alpes Sudtrain
- Take the train from Valence Tgv Rhone-Alpes Sud to Avignon Tgvtrain
- Take the train from Avignon Tgv to Aix En Provence Tgvtrain
- Fly from Marseille Provence Airport (MRS) to Palermo Airport (PMO)plane MRS - PMO
8h 2m€95–344Train, train to Milano Malpensa Airport, fly
- Take the train from Grenoble to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Palermo Airport (PMO)plane MXP - PMO
9h 54m€70–326Bus, car ferry
- Take the bus from Grenoble to Genoabus 1501 / ...
- Take the carferry from Port of Genoa to Port of Palermocarferry
27h 45m€130–198Train, bus
- Take the train from Grenoble to Chambery Challes Les Eauxtrain Ter
- Take the train from Chambery Challes Les Eaux to Milano P.Garibalditrain Tgv
- Take the bus from Milano - Famagosta to Palermo Piazza Cairolibus
29h 30m€287–435
Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO) flights
Questions & Answers
The cheapest way to get from Grenoble to Palermo is to train and fly which costs €55 - €300 and takes 8h 36m.
The fastest way to get from Grenoble to Palermo is to train and fly which takes 5h 48m and costs €80 - €300.
No, there is no direct bus from Grenoble to Palermo. However, there are services departing from Grenoble and arriving at Palermo via Turin. The journey, including transfers, takes approximately 29h.
The distance between Grenoble and Palermo is 1213 km.
The best way to get from Grenoble to Palermo without a car is to train and ferry which takes 20h 16m and costs .
It takes approximately 5h 48m to get from Grenoble to Palermo, including transfers.
Grenoble to Palermo bus services, operated by FlixBus, depart from Grenoble station.
Grenoble to Palermo bus services, operated by FlixBus, arrive at Turin station.
Book your Grenoble to Palermo bus tickets online with Omio and FlixBus.
There are 6324+ hotels available in Palermo.
What companies run services between Grenoble, France and Palermo, Italy?
You can take a bus from Grenoble to Palermo via Turin in around 29h.
- Website
- ryanair.com
Flights from Turin Caselle Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €40–190
Flights from Turin Caselle Airport to Palermo Airport via Cagliari
- Ave. Duration
- 4h
- When
- Monday
- Estimated price
- €40–190
Flights from Marseille Provence Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- €45–200
Flights from Marseille Provence Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 5m
- When
- Thursday, Monday, and Saturday
- Estimated price
- €45–200
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–150
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Grenoble to Lyon-Saint Exupery Tgv
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €40–65
- Website
- TGV inOui
Train from Valence Tgv Rhone-Alpes Sud to Avignon Tgv
- Ave. Duration
- 31 min
- Frequency
- Every 2 hours
- Estimated price
- €26–45
- Website
- TGV inOui
Train from Avignon Tgv to Aix En Provence Tgv
- Ave. Duration
- 21 min
- Frequency
- Every 30 minutes
- Estimated price
- €14–24
- Website
- TGV inOui
Train from Chambery Challes Les Eaux to Milano P.Garibaldi
- Ave. Duration
- 4h 4m
- Frequency
- Every 4 hours
- Estimated price
- €65–110
- Website
- TGV inOui
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Grenoble to Turin
- Ave. Duration
- 3h 55m
- Frequency
- Every 4 hours
- Estimated price
- €17–29
- Website
- Flixbus
Bus from Turin to Palermo
- Ave. Duration
- 24h 5m
- Frequency
- Once daily
- Estimated price
- €130–210
- Website
- Flixbus
Bus from Grenoble to Genoa
- Ave. Duration
- 5h 50m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Travelling by boat in Italy
Read the travel guide










