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How to get fromGrenoble to Sienaby train (TGV, Trenitalia), bus, car, train, or plane

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There are 6 ways to get from Grenoble to Siena by train (TGV, Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Grenoble to Chambery Challes Les Eauxtrain train Ter
    2. Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain train Tgv
    3. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    9h 48m
    €101–247

  2. Bus via Turin

    cheapest
    1. Take the bus from Grenoble to Turinbus bus FlixBus N740 / ...
    2. Take the bus from Turin Corso Vittorio Emanuele II to Siena Central Train Stationbus bus Itabus
    13h 50m
    €50–115

  3. Bus

    1. Take the bus from Grenoble to Florence Villa Constanza Bus Stationbus bus 1501
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    10h 25m
    €52–84

  4. Drive 662.3 km

    1. Drive from Grenoble to Sienacar car 662.3 km
    7h 20m
    €104–150

  5. Train, fly to Florence Peretola Airport

    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Florence Peretola Airport (FLR)plane plane LYS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 38m
    €101–287

  6. Train, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Grenoble to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane LYS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 22m
    €109–302

Grenoble to Siena by train

Calendar69Weekly Trains
Duration9h 48mAverage Duration
Ticket€101Cheapest Price
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Questions & Answers

Map of how to get from Grenoble to Siena.ExpandLaunch map view
  • Distance: 801.3 km
  • Duration: 9h 48m

What companies run services between Grenoble, France and Siena, Italy?

You can take a train from Grenoble to Siena via Chambery Challes Les Eaux, Torino Porta Susa, and Firenze S.M.N. in around 9h 48m. Alternatively, you can take a bus from Grenoble to Siena via Florence Villa Constanza Bus Station in around 10h 25m.

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