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How to get fromGreyhound Bus Station to Knoxvilleby car, plane, taxi, bus, train, or shuttle

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There are 9 ways to get from Greyhound Bus Station to Knoxville by car, plane, taxi, bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly to Mcghee Tyson Airport

    best
    1. Drive from Greyhound Bus Station to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS)plane plane SFB - TYS
    3h 56m
    $181–744

  2. Drive to Orlando Sanford, fly to Asheville Regional Airport, drive

    cheapest
    1. Drive from Greyhound Bus Station to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    5h 52m
    $93–399

  3. Taxi, bus, train via Orlando

    1. Take the taxi from Greyhound Bus Station to Ocala, FLtaxi taxi
    2. Take the bus from Ocala, FL to Orlando - RedCoach Station, FLbus bus
    3. Take the train from Orlando to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 9m
    $623–1,088

  4. Taxi, bus

    1. Take the taxi from Greyhound Bus Station to Wildwood Amtrak Stationtaxi taxi
    2. Take the bus from Wildwood Amtrak Station to Jacksonvillebus bus
    3. Take the bus from Jacksonville to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    42h 27m
    $432–604

  5. Drive 581 mi

    1. Drive from Greyhound Bus Station to Knoxvillecar car 581 mi
    10h 12m
    $106–154

  6. Taxi, shuttle to Orlando, fly to Mcghee Tyson Airport

    1. Take the taxi from Greyhound Bus Station to Sleep Inntaxi taxi
    2. Take a shuttle bus from Sleep Inn to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Mcghee Tyson Airport (TYS)plane plane MCO - TYS
    5h 18m
    $340–876

  7. Taxi, bus to Gainesville Regional Airport, fly to Mcghee Tyson Airport

    1. Take the taxi from Greyhound Bus Station to Ocala, FLtaxi taxi
    2. Take the bus from Ocala, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    3. Fly from Gainesville Regional Airport (GNV) to Mcghee Tyson Airport (TYS)plane plane GNV - TYS
    8h 28m
    $282–829

  8. Taxi, bus, train

    1. Take the taxi from Greyhound Bus Station to Ocala, FLtaxi taxi
    2. Take the bus from Ocala, FL to Kissimmee -1471 East Osceola Parkwaybus bus
    3. Take the train from Kissimmee Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the bus from New York to Knoxvillebus bus Nyc
    41h 32m
    $678–1,180

  9. Taxi, bus via Washington

    1. Take the taxi from Greyhound Bus Station to Ocala, FLtaxi taxi
    2. Take the bus from Ocala, FL to West Palm Beach, FLbus bus
    3. Take the bus from West Palm Beach Bus Station to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to New York City Chinatownbus bus
    5. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    2d
    $468–715

Orlando Sanford (SFB) to Mcghee Tyson Airport (TYS) flights

Calendar11Weekly Planes
Duration1h 38mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from Greyhound Bus Station to Knoxville.ExpandLaunch map view
  • Distance: 614.7 mi
  • Duration: 3h 56m

What companies run services between Greyhound Bus Station, FL, USA and Knoxville, TN, USA?

There is no direct connection from Greyhound Bus Station to Knoxville. However, you can drive to Orlando-Sanford-Airport-SFB airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take the taxi to Ocala, FL, take the bus to Orlando - RedCoach Station, FL, take the line 42 bus to Office Ct & Sand Lake Sunrail, walk to Sand Lake Road, take the train to Orlando Health/Amtrak, walk to Orlando, take the train to Ny Moynihan Train Hall At Penn Station, walk to 34 St-Herald Sq, take the subway to East Broadway, walk to New York, NY, take the bus to Knoxville, TN, then take the taxi to Knoxville.

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