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How to get fromGriffith to St. Louisby train (Amtrak), bus (Flixbus), car, taxi, train, subway, or plane

Find Transport to St. Louis

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There are 5 ways to get from Griffith to St. Louis by train (Amtrak), bus (Flixbus), car, taxi, train, subway, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Gary/Chicago Airport to Van Buren St.train train Westbound to Chicago / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    7h 1m
    $185–280

  2. Drive  288.3 mi

    cheapest
    1. Drive from Griffith to St. Louiscar car 288.3 mi
    5h 9m
    $53–76

  3. Bus (Flixbus)

    1. Take the bus from Chicago to St Louis Bus Stationbus bus FlixBus N2521
    7h 48m
    $82–116

  4. Taxi, train, subway to Chicago Midway International Airport, fly

    1. Take the taxi from Griffith to Gary/Chicago Airporttaxi taxi
    2. Take the train from Gary/Chicago Airport to Museum Campus/11th Street Sationtrain train
    3. Take the subway from Roosevelt to Midwaysubway subway
    4. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 33m
    $107–545

  5. Taxi, train to Chicago O'Hare International Airport, fly

    1. Take the taxi from Griffith to Gary/Chicago Airporttaxi taxi
    2. Take the train from Gary/Chicago Airport to Van Buren St.train train
    3. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 59m
    $357–745

Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL) flights

Calendar31Weekly Planes
Duration1h 11mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Griffith to St. Louis.ExpandLaunch map view
  • Distance: 315.7 mi
  • Duration: 7h 1m

What companies run services between Griffith, IN, USA and St. Louis, MO, USA?

You can take a vehicle from Griffith to St. Louis via Gary/Chicago Airport, Van Buren St., Michigan & Van Buren, Clinton & Jackson, and Chicago Union Station in around 7h 1m. Alternatively, Flixbus USA operates a bus from Chicago to St Louis Bus Station 5 times a week. Tickets cost $45–70 and the journey takes 5h 40m.

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