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How to get fromGroton to Buffaloby taxi, plane, bus (Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Groton to Buffalo by taxi, plane, bus (Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Manchester Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the taxi from Groton to Manchester-Airport-MHTtaxi taxi
    2. Fly from Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF)plane plane MHT - BUF
    5h 29m
    $291–929

  2. Drive 419.7 mi

    cheapest
    1. Drive from Groton to Buffalocar car 419.7 mi
    8h 26m
    $77–111

  3. Bus

    1. Take the bus from Ayer MA to Bostonbus bus Greyhound US0256S
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    12h 31m
    $97–182

  4. Train

    1. Take the train from Ayer to Portertrain train Fitchburg Line
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    15h 21m
    $177–494

  5. Train to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Ayer to North Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    5h 24m
    $116–614

  6. Train to Boston Logan Airport, fly to Rochester, bus

    1. Take the train from Ayer to North Stationtrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h 28m
    $134–629

  7. Bus via Ithaca

    1. Take the bus from Ayer MA to Springfield Union Stationbus bus
    2. Take the bus from Springfield Union Station to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    14h 55m
    $103–228

Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF) flights

Calendar66Weekly Planes
Duration5h 2mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Groton to Buffalo.ExpandLaunch map view
  • Distance: 409.8 mi
  • Duration: 5h 29m

What companies run services between Groton, MA, USA and Buffalo, NY, USA?

You can take a vehicle from Groton to Buffalo via Ayer MA and Boston in around 12h 31m. Alternatively, you can take a vehicle from Groton to Buffalo via Ayer, Porter, Porter, South Station, Boston, and Buffalo Depew Station in around 15h 21m.

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