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How to get fromGuadalajara to Santa Anaby plane, bus, car, or train

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There are 8 ways to get from Guadalajara to Santa Ana by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Miguel Hidalgo Y Costilla Guadalajara International Airport to John Wayne Airport Orange County

    best
    1. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to John Wayne Airport Orange County (SNA)plane plane GDL - SNA
    7h 43m
    $137–543

  2. Bus

    cheapest
    1. Take the bus from Guadalajara to Santa Anabus bus
    33h 56m
    $81–201

  3. Drive  1,470.1 mi

    1. Drive from Guadalajara to Santa Anacar car 1,470.1 mi
    26h 56m
    $269–388

  4. Fly Miguel Hidalgo Y Costilla Guadalajara International Airport to Tijuana International Airport, bus

    1. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Tijuana International Airport (TIJ)plane plane GDL - TIJ
    2. Take the bus from Tijuana Aeropuerto, B.C. to Santa Anabus bus
    7h 43m
    $118–273

  5. Fly Miguel Hidalgo Y Costilla Guadalajara International Airport to Los Angeles International Airport, train

    1. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Los Angeles International Airport (LAX)plane plane GDL - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    8h 19m
    $129–311

  6. Fly Miguel Hidalgo Y Costilla Guadalajara International Airport to Ontario International Airport, train

    1. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Ontario International Airport (ONT)plane plane GDL - ONT
    2. Take the train from San Bernardino Depot to Santa Anatrain train
    9h 36m
    $109–435

  7. Bus to Licenciado Gustavo Díaz Ordaz International Airport, fly to John Wayne Airport Orange County

    1. Take the bus from Terminal Milenio Zapopan to Puerto Vallartabus bus
    2. Fly from Licenciado Gustavo Díaz Ordaz International Airport (PVR) to John Wayne Airport Orange County (SNA)plane plane PVR - SNA
    9h 57m
    $176–693

  8. Bus via Tijuana

    1. Take the bus from Nueva Central Camionera de Guadalajara Mod 7 to Tijuanabus bus
    2. Take the bus from Tijuana Central, B.C. to Santa Anabus bus Lxus 3126 / ...
    39h 29m
    $181–326

Guadalajara to Santa Ana by bus

Calendar7Weekly Buses
Duration33h 56mAverage Duration
Ticket$81Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guadalajara to Santa Ana.ExpandLaunch map view
  • Distance: 1,289.4 mi
  • Duration: 7h 43m

What companies run services between Guadalajara, Mexico and Santa Ana, CA, USA?

American Airlines, Volaris, and three other airlines fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to John Wayne Airport Orange County (SNA) 4 times a day. Alternatively, ACN Autobuses operates a bus from Guadalajara to Santa Ana once daily. Tickets cost $80–200 and the journey takes 32h 35m.

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