There are 9 ways to get from Guadalupe to Calexico by train, bus, bus (Flixbus), car, plane, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Guadalupe Amtrak Station to San Diego Old Town Transportation Centertrain Pacific Surfliner
- Take the bus from San Diego Greyhound Bus Stop to Calexico Bus Stationbus Greyhound US0851S
11h 51m$120–250Bus via Santa Barbara
cheapest- Take the bus from Santa Maria Transit Center to Chapala at Figueroabus
- Take the bus from Santa Barbara Bus Stop to Los Angeles Union Stationbus
- Take the bus from Los Angeles Downtown to Calexico Bus Stationbus
13h 59m$59–97Drive 385.7 mi
- Drive from Guadalupe to Calexicocar 385.7 mi
6h 51m$71–102Train to Los Angeles International Airport, fly to Imperial County Airport
- Take the train from Guadalupe Amtrak Station to Los Angelestrain
- Fly from Los Angeles International Airport (LAX) to Imperial County Airport (IPL)plane LAX - IPL
8h 49m$184–782Train, bus via Los Angeles
- Take the train from Guadalupe Amtrak Station to Los Angelestrain
- Take the train from Los Angeles to Yuma Amtraktrain
- Take the bus from Yuma County Area Transit to Calexico Bus Stationbus
13h 44m$146–317Bus
- Take the bus from Santa Maria Airport, CA to Los Angeles Airport, CAbus
- Take the bus from Los Angeles Union Station to Calexico Bus Stationbus Greyhound US0850
14h 18m$125–187Bus to Santa Barbara Municipal Airport, fly to San Diego International Airport, bus
- Take the bus from Santa Maria Airport, CA to Santa Barbara Airportbus
- Fly from Santa Barbara Municipal Airport (SBA) to San Diego International Airport (SAN)plane SBA - SAN
- Take the bus from San Diego Greyhound Bus Stop to Calexico Bus Stationbus
9h 36m$157–339Fly San Luis Obispo County Regional Airport to San Diego International Airport, bus
- Fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN)plane SBP - SAN
- Take the bus from San Diego Greyhound Bus Stop to Calexico Bus Stationbus
9h 49m$199–410Fly San Luis Obispo County Regional Airport to Imperial County Airport
- Fly from San Luis Obispo County Regional Airport (SBP) to Imperial County Airport (IPL)plane SBP - IPL
10h 17m$100–390
Guadalupe to Calexico by train and bus
Questions & Answers
The cheapest way to get from Guadalupe to Calexico is to bus via Santa Barbara which costs $55 - $100 and takes 13h 59m.
The fastest way to get from Guadalupe to Calexico is to drive which takes 6h 51m and costs $70 - $110.
No, there is no direct bus from Guadalupe station to Calexico station. However, there are services departing from Guadalupe Amtrak Station and arriving at Calexico Bus Station via Santa Maria Transit Center, Chapala & Anapamu, Santa Barbara Bus Stop and Los Angeles Downtown. The journey, including transfers, takes approximately 13h 59m.
The distance between Guadalupe and Calexico is 450 miles. The road distance is 387.9 miles.
The best way to get from Guadalupe to Calexico without a car is to train and bus which takes 11h 51m and costs $120 - $250.
It takes approximately 11h 51m to get from Guadalupe to Calexico, including transfers.
Guadalupe to Calexico bus services, operated by Clean Air Express, depart from Santa Maria Transit Center station.
The best way to get from Guadalupe to Calexico is to bus via Santa Barbara which takes 13h 59m and costs $55 - $100. Alternatively, you can fly, which costs $95 - $390 and takes 10h 17m.
Guadalupe to Calexico bus services, operated by Clean Air Express, arrive at Chapala at Figueroa station.
Yes, the driving distance between Guadalupe to Calexico is 388 miles. It takes approximately 6h 51m to drive from Guadalupe to Calexico.
What companies run services between Guadalupe, CA, USA and Calexico, CA, USA?
You can take a bus from Guadalupe Amtrak Station to Calexico Bus Station via Santa Maria Transit Center, Chapala at Figueroa, Chapala & Anapamu, State & Yanonali, Santa Barbara Bus Stop, Los Angeles Union Station, and Los Angeles Downtown in around 13h 59m. Alternatively, United Airlines, Southern Airways Express, and American Airlines fly from San Luis Obispo County Regional Airport (SBP) to Imperial County Airport (IPL) 4 times a day.
- Website
- iflysouthern.com
Flights from Los Angeles International Airport to Imperial County Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $85–310
Flights from San Luis Obispo County Regional Airport to Imperial County Airport via Los Angeles International Airport
- Ave. Duration
- 6h 26m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–370
Flights from San Luis Obispo County Regional Airport to Imperial County Airport via Phoenix
- Ave. Duration
- 7h 53m
- When
- Every day
- Estimated price
- $60–340
Flights from San Luis Obispo County Regional Airport to Imperial County Airport via San Francisco, Los Angeles International Airport
- Ave. Duration
- 8h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–330
- Website
- alaskaair.com
Flights from Santa Barbara Municipal Airport to San Diego International Airport
- Ave. Duration
- 1h 4m
- When
- Every day
- Estimated price
- $75–220
Flights from San Luis Obispo County Regional Airport to San Diego International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $170–350
- Website
- southwest.com
Flights from Santa Barbara Municipal Airport to San Diego International Airport
- Ave. Duration
- 53 min
- When
- Every day
- Estimated price
- $29–210
- Website
- united.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport via Los Angeles International Airport
- Ave. Duration
- 3h 28m
- When
- Saturday, Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $35–240
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Guadalupe Amtrak Station to San Diego Old Town Transportation Center
- Ave. Duration
- 8h 6m
- Frequency
- 3 times a day
- Estimated price
- $100–210
- Website
- Amtrak
Train from Guadalupe Amtrak Station to Los Angeles
- Ave. Duration
- 5h 4m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- Amtrak
Train from Guadalupe Amtrak Station to Los Angeles
- Ave. Duration
- 5h 4m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- Amtrak
Train from Los Angeles to Yuma Amtrak
- Ave. Duration
- 4h 47m
- Frequency
- 6 times a week
- Estimated price
- $75–170
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Diego Greyhound Bus Stop to Calexico Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- Greyhound
Bus from Yuma County Area Transit to Calexico Bus Station
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Los Angeles Union Station to Calexico Bus Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $30–70
- Website
- Greyhound
Bus from San Diego Greyhound Bus Stop to Calexico Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- Greyhound
Bus from San Diego Greyhound Bus Stop to Calexico Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $19–40
- Website
- Greyhound
- Phone
- (805) 692-1902
- [email protected]
- Website
- Clean Air Express
Bus from Santa Maria Transit Center to Chapala at Figueroa
- Ave. Duration
- 1h 37m
- Frequency
- Once daily
- Estimated price
- $7–8
- Website
- Clean Air Express
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Santa Barbara Bus Stop to Los Angeles Union Station
- Ave. Duration
- 2h 25m
- Frequency
- 4 times a week
- Estimated price
- $14–25
- Schedules at
- Flixbus USA
Bus from Los Angeles Downtown to Calexico Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- 6 times a week
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from Yuma County Area Transit to Calexico Bus Station
- Ave. Duration
- 1h 10m
- Frequency
- 6 times a week
- Estimated price
- $8–15
- Schedules at
- Flixbus USA
Bus from Los Angeles Union Station to Calexico Bus Station
- Ave. Duration
- 5h 5m
- Frequency
- 6 times a week
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
- Phone
- +1 800-470-8818
- [email protected]
- Website
- Central Coast Shuttle
Bus from Santa Maria Airport, CA to Los Angeles Airport, CA
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- $85–105
- Website
- Central Coast Shuttle
- one way non-prepaid
- $90–105
- One-way prepaid 48 hours advance
- $85–100
Bus from Santa Maria Airport, CA to Santa Barbara Airport
- Ave. Duration
- 1h 13m
- Frequency
- Every 4 hours
- Estimated price
- $60–75
- Website
- Central Coast Shuttle
- one way non-prepaid
- $65–75
- One-way prepaid 48 hours advance
- $60–70
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 96+ hotels available in Calexico.









