There are 4 ways to get from Guayaquil to Panama by plane, bus, taxi, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Tocumen International Airport
best- Fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY)plane GYE - PTY
2h 57m$273–513Fly to David
cheapest- Fly from José Joaquín De Olmedo International Airport (GYE) to David (DAV)plane GYE - DAV
4h 42m$126–611Bus, taxi, ferry, drive
- Take the bus from Terminal Terrestre de Guayaquil to Tulcánbus
- Take the bus from Terminal de Transporte Ipiales to Terminal del Surbus
- Take the taxi from Medellín to Cartagenataxi
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
8d 2h$1,275–1,329Bus, ferry, drive
- Take the bus from Guayaquil to Terminal Terrestre Quitumbebus
- Take the bus from Terminal Terrestre Quitumbe to Tulcánbus
- Take the bus from Terminal Ipiales to Terminal de Pastobus
- Take the bus from Terminal de Pasto to Terminal Salitrebus
- Take the bus from Terminal Salitre to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
8d 17h$828–903
José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) flights
Comparing Your Travel Options
The cheapest way to get from Guayaquil to Panama is to fly which costs $120 - $650 and takes 4h 42m.
The fastest way to get from Guayaquil to Panama is to fly which takes 2h 57m and costs $270 - $550.
The distance between Guayaquil and Panama is 1271 km.
It takes approximately 2h 57m to get from Guayaquil to Panama, including transfers.
There are 877+ hotels available in Panama.
What companies run services between Guayaquil, Ecuador and Panama?
Copa Airlines and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) every 4 hours.
- Website
- copaair.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $70–380
Flights from José Joaquín De Olmedo International Airport to David via Tocumen International Airport
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $120–650
- Website
- avianca.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $230–480
- Phone
- +593 95 885 1254
- [email protected]
- Website
- microsancristobal.com
Bus from Terminal Terrestre de Guayaquil to Tulcán
- Ave. Duration
- 13h
- Frequency
- Every 4 hours
- Estimated price
- $19–22
- Book at
- busplace.com
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminal de Transporte Ipiales to Terminal del Sur
- Ave. Duration
- 19h 39m
- Frequency
- Every 4 hours
- Estimated price
- $40–85
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +593 98 875 2804
- [email protected]
- Website
- Cooperativa de Transportes Aerotaxi
Bus from Guayaquil to Terminal Terrestre Quitumbe
- Ave. Duration
- 9h
- Frequency
- Every 4 hours
- Estimated price
- $11–12
- Website
- Cooperativa de Transportes Aerotaxi
- Website
- Cooperativa de Transportes Aerotaxi
- Phone
- +593 96 297 2979
- [email protected]
- Website
- Trans Esmeraldas S.A.
Bus from Guayaquil to Terminal Terrestre Quitumbe
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- $15–22
- Schedules at
- Trans Esmeraldas S.A.
- Phone
- +593 062980728
- [email protected]
- Website
- Cooperativa Tax Gacela
Bus from Terminal Terrestre Quitumbe to Tulcán
- Ave. Duration
- 5h
- Frequency
- Hourly
- Estimated price
- $6–10
- Schedules at
- Cooperativa Tax Gacela
- Phone
- +57 314 8300867
- [email protected]
- Website
- cootranar.com
Bus from Terminal Ipiales to Terminal de Pasto
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $8
- Schedules at
- cootranar.com
- Book at
- redbus.co
- Phone
- +57 601 424 9090
- [email protected]
- Website
- Continental Bus
Bus from Terminal de Pasto to Terminal Salitre
- Ave. Duration
- 18h 40m
- Frequency
- Every 4 hours
- Estimated price
- $48
- Schedules at
- Continental Bus
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 23h
- Frequency
- Every 3 hours
- Estimated price
- $60–85
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $60–85
- Phone
- +57 310 7883333
- [email protected]
- Website
- concordeoficial.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $40–95
- Schedules at
- concordeoficial.com
- Book at
- concordeoficial.com
- Phone
- +57 310 704 0425
- [email protected]
- Website
- Blue Sailing
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
- Ave. Duration
- 13h 10m
- Estimated price
- $501
Tax Individual
- Phone
- +57 604 444 4444
- Website
- tax-individual.com.co
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