There are 9 ways to get from Guayaquil to San Blas by plane, unknown, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly José Joaquín De Olmedo International Airport to Tocumen International Airport, travel
best- Fly from José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY)plane GYE - PTY
- Walk from Chepo to San Blasunknown
4h 15mBus, ferry, travel via Cúcuta
- Take the bus from Guayaquil to Quito Terminal Carcelénbus
- Take the bus from Terminal Terrestre Quitumbe to Cúcutabus
- Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to El Porvenirferry
- Walk from El Porvenir to San Blasunknown
6d 23hFly José Joaquín De Olmedo International Airport to Panama Pacific International Airport, bus, travel
- Fly from José Joaquín De Olmedo International Airport (GYE) to Panama Pacific International Airport (BLB)plane GYE - BLB
- Take the bus from Albrook to El Llanobus
- Walk from El Llano to San Blasunknown
7h 38mBus, bus to Eloy Alfaro International Airport, fly to Tocumen International Airport, travel
- Take the bus from Guayaquil to Montañitabus
- Take the bus from Montañita to Manta Terminal Terrestrebus
- Fly from Eloy Alfaro International Airport (MEC) to Tocumen International Airport (PTY)plane MEC - PTY
- Walk from Chepo to San Blasunknown
9h 58mBus to Mariscal Sucre International Airport, fly to Tocumen International Airport, travel
- Take the bus from Guayaquil to Quito Terminal Carcelénbus
- Fly from Mariscal Sucre International Airport (UIO) to Tocumen International Airport (PTY)plane UIO - PTY
- Walk from Chepo to San Blasunknown
12h 30mBus to Cuenca, fly to Tocumen International Airport, travel
- Take the bus from Terminal Terrestre de Guayaquil to Cuencabus
- Fly from Cuenca (CUE) to Tocumen International Airport (PTY)plane CUE - PTY
- Walk from Chepo to San Blasunknown
11h 25mBus to Santa Rosa Regional Airport, fly to Tocumen International Airport, travel
- Take the bus from Terminal Terrestre de Guayaquil to Santa Rosabus
- Fly from Santa Rosa Regional Airport (ETR) to Tocumen International Airport (PTY)plane ETR - PTY
- Walk from Chepo to San Blasunknown
14h 24mBus, ferry, travel
- Take the bus from Guayaquil to Terminal Terrestre Quitumbebus
- Take the bus from Terminal Terrestre Quitumbe to Rumichacabus
- Take the bus from Terminales de Transportes de Ipiales to Terminal Salitrebus
- Take the bus from Terminal Salitre to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to El Porvenirferry
- Walk from El Porvenir to San Blasunknown
7d 13hBus, ferry, travel #2
- Take the bus from Terminal Terrestre de Guayaquil to Cúcutabus
- Take the bus from Terminal Cúcuta to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to El Porvenirferry
- Walk from El Porvenir to San Blasunknown
7d 15h
José Joaquín De Olmedo International Airport (GYE) to Tocumen International Airport (PTY) flights
Questions & Answers
The distance between Guayaquil and San Blas is 1339 km.
It takes approximately 4h 15m to get from Guayaquil to San Blas, including transfers.
There are 49+ hotels available in San Blas.
What companies run services between Guayaquil, Ecuador and San Blas, Panama?
There is no direct connection from Guayaquil to San Blas. However, you can fly to Tocumen International Airport (PTY), walk to Aeropuerto Internacional de Tocumen, take the shuttle to Chepo, then travel to San Blas. Alternatively, you can take a bus from Guayaquil to San Blas via Quito Terminal Carcelén, El Labrador, Terminal Terrestre Quitumbe, Cúcuta, Terminal Cúcuta, Terminal de Transporte de Cartagena, Cartagena, and El Porvenir in around 6d 23h.
- Website
- copaair.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $65–340
Flights from Eloy Alfaro International Airport to Tocumen International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $70–380
Flights from Mariscal Sucre International Airport to Tocumen International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $55–300
Flights from Cuenca to Tocumen International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 4h 56m
- When
- Tuesday to Friday
- Estimated price
- $75–380
Flights from Cuenca to Tocumen International Airport via José Joaquín De Olmedo International Airport
- Ave. Duration
- 6h 16m
- When
- Monday, Tuesday, and Thursday
- Estimated price
- $75–380
Flights from Santa Rosa Regional Airport to Tocumen International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 8h 1m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- $75–380
Flights from Santa Rosa Regional Airport to Tocumen International Airport via Mariscal Sucre International Airport, José Joaquín De Olmedo International Airport
- Ave. Duration
- 6h 25m
- When
- Monday
- Estimated price
- $95–440
- Website
- klm.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $65–340
Flights from Mariscal Sucre International Airport to Tocumen International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $55–300
Flights from Mariscal Sucre International Airport to Tocumen International Airport via José Joaquín De Olmedo International Airport
- Ave. Duration
- 4h 35m
- When
- Tuesday to Sunday
- Estimated price
- $70–360
Flights from Cuenca to Tocumen International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 3h 42m
- When
- Tuesday
- Estimated price
- $75–380
- Website
- avianca.com
Flights from José Joaquín De Olmedo International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 5h 7m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $200–500
Flights from Mariscal Sucre International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $220–270
- Website
- copaair.com
Flights from José Joaquín De Olmedo International Airport to Panama Pacific International Airport via Bogota
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $210–850
Flights from José Joaquín De Olmedo International Airport to Panama Pacific International Airport via Tocumen International Airport, Medellin Jose Marie Cordova
- Ave. Duration
- 8h 58m
- When
- Tuesday, Friday, and Sunday
- Estimated price
- $110–550
Flights from José Joaquín De Olmedo International Airport to Panama Pacific International Airport via Mariscal Sucre International Airport
- Ave. Duration
- 3h 59m
- When
- Thursday
- Estimated price
- $270–950
- Phone
- +593 96 297 2979
- [email protected]
- Website
- transesmeraldas.com.ec
Bus from Guayaquil to Quito Terminal Carcelén
- Ave. Duration
- 5h 34m
- Frequency
- Twice daily
- Estimated price
- $16–22
- Schedules at
- transesmeraldas.com.ec
Bus from Guayaquil to Quito Terminal Carcelén
- Ave. Duration
- 5h 34m
- Frequency
- Twice daily
- Estimated price
- $16–22
- Schedules at
- transesmeraldas.com.ec
Bus from Guayaquil to Terminal Terrestre Quitumbe
- Ave. Duration
- 5h 6m
- Frequency
- Twice daily
- Estimated price
- $15–22
- Schedules at
- transesmeraldas.com.ec
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre Quitumbe to Cúcuta
- Ave. Duration
- 20h 36m
- Frequency
- Once daily
- Estimated price
- $110–140
- Website
- https://www.facebook.com/lineasdelosandesve/
Bus from Terminal Terrestre Quitumbe to Rumichaca
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $30–40
- Website
- https://www.facebook.com/lineasdelosandesve/
Bus from Terminal Terrestre de Guayaquil to Cúcuta
- Ave. Duration
- 44h
- Frequency
- Once daily
- Estimated price
- $130–240
- Website
- https://www.facebook.com/lineasdelosandesve/
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- $45–65
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $45–65
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 23h
- Frequency
- Every 3 hours
- Estimated price
- $60–85
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $60–85
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 30m
- Frequency
- 4 times a day
- Estimated price
- $45–65
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $45–65
- Phone
- 01 800 051 8001
- [email protected]
- Website
- expresobrasilia.com
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 2m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- $40–60
Bus from Terminal Cúcuta to Terminal de Transporte de Cartagena
- Ave. Duration
- 17h 2m
- Frequency
- Twice daily
- Estimated price
- $40–65
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- $40–60
- Phone
- +507 303 3030
- Website
- grantnt.com
Bus from Albrook to El Llano
- Ave. Duration
- 1h 42m
- Frequency
- 5 times a day
- Schedules at
- grantnt.com
- Phone
- +593 0987472459
- [email protected]
- Website
- clp.com.ec
Bus from Guayaquil to Montañita
- Ave. Duration
- 1h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $6–8
- Schedules at
- clp.com.ec
- Phone
- +593 99 436 5377
- [email protected]
- Website
- facebook.com
Bus from Montañita to Manta Terminal Terrestre
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- $4–6
- Schedules at
- movilidadmanta.gob.ec
- Phone
- +593 99 144 1474
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- $8–11
- Schedules at
- facebook.com
- Book at
- ecuabuses.com
- Phone
- +593 09 9900 8843
- [email protected]
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 3h 35m
- Frequency
- 5 times a day
- Estimated price
- $7–10
- Schedules at
- facebook.com
- Phone
- +593 98 453 6454
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Cuenca
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $11–35
- Book at
- redbus.pe
- Phone
- +593 93 999 0918
- [email protected]
- Website
- facebook.com
Bus from Terminal Terrestre de Guayaquil to Santa Rosa
- Ave. Duration
- 3h 45m
- Frequency
- 5 times a day
- Estimated price
- $7–10
- Schedules at
- facebook.com
- Road
- $7–10
- Phone
- +593 06 2958921
- [email protected]
- Website
- facebook.com
Bus from Guayaquil to Terminal Terrestre Quitumbe
- Ave. Duration
- 9h
- Frequency
- Every 4 hours
- Estimated price
- $13–26
- Website
- https://www.facebook.com/cooperativa.transportes.aerotaxi
- Phone
- +57 601 424 9090
- [email protected]
- Website
- continentalbus.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $58
- Schedules at
- continentalbus.com.co
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $45–80
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +57 310 7883333
- [email protected]
- Website
- concordeoficial.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $65–95
- Schedules at
- concordeoficial.com
- Book at
- concordeoficial.com
- Phone
- +57 310 704 0425
- [email protected]
- Website
- bluesailing.net
Ferry from Cartagena to El Porvenir
- Ave. Duration
- 5d
- Frequency
- On demand
- Estimated price
- $700
- Website
- https://bluesailing.net/en_us/
Ferry from Cartagena to El Porvenir
- Ave. Duration
- 5d
- Frequency
- On demand
- Estimated price
- $700
- Website
- https://bluesailing.net/en_us/
Ferry from Cartagena to El Porvenir
- Ave. Duration
- 5d
- Frequency
- On demand
- Estimated price
- $700
- Website
- https://bluesailing.net/en_us/
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How do I buy a London Underground ticket?, What are the different types of Renfe trains in Spain?, and Need to know: Jadrolinija - to help you get the most out of your next trip.










































