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How to get fromGuayaquil to Santa Cruz de la Sierraby plane, bus, car, or shuttle

Find Transport to Santa Cruz de la Sierra

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There are 5 ways to get from Guayaquil to Santa Cruz de la Sierra by plane, bus, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI)plane plane GYE - VVI
    7h 20m
    $410–665

  2. Bus, Tour

    cheapest
    1. Take the bus from Terminal Terrestre de Guayaquil to Tumbesbus bus
    2. Take the bus from Tumbes to Limabus bus
    3. Take the bus from Terminal Ronco to Punobus bus
    4. Take a shuttle bus from Puno to La Pazshuttle bus
    5. Take the bus from La Paz to Santa Cruzbus bus
    3d 7h
    $161–261

  3. Bus, drive

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    2. Take the bus from Lima Terminal Excluciva to Tacnabus bus
    3. Drive from Tacna to El Roble / Dr. Amador Neghmecar car
    4. Take the bus from Terminal Rodoviario de Arica to Huarabus bus
    5. Take the bus from Huara to Iquiquebus bus
    6. Take the bus from Iquique to Santa Cruzbus bus
    2d 19h

  4. Drive 3,717.2 km

    1. Drive from Guayaquil to Santa Cruz de la Sierracar car 3,717.2 km
    2d 4h
    $211–305

  5. Bus

    1. Take the bus from Terminal Terrestre de Guayaquil to Tumbesbus bus
    2. Take the bus from Tumbes to Gran Terminal Terrestre Plaza Nortebus bus
    3. Take the bus from Oltursa Lima Terminal to La Pazbus bus
    4. Take the bus from La Paz to Santa Cruzbus bus
    3d
    $192–283

José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI) flights

Calendar23Weekly Planes
Duration9h 44mAverage Duration
Ticket$203Cheapest Price
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Questions & Answers

Map of how to get from Guayaquil to Santa Cruz de la Sierra.ExpandLaunch map view
  • Distance: 2,532.2 km
  • Duration: 7h 20m

What companies run services between Guayaquil, Ecuador and Santa Cruz de la Sierra, Bolivia?

LATAM Chile, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to Viru Viru International Airport (VVI) 3 times a day. Alternatively, you can take a bus from Terminal Terrestre de Guayaquil to Santa Cruz via Tumbes, Tumbes, Gran Terminal Terrestre Plaza Norte, Oltursa Lima Terminal, and La Paz in around 3d.

Airlines
Bus operators

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