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How to get fromGuayaquil to Santa Isabelby plane, bus, car, or taxi

Find Transport to Santa Isabel

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There are 7 ways to get from Guayaquil to Santa Isabel by plane, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to São Paulo–Guarulhos International Airport

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU)plane plane GYE - GRU
    10h 15m
    R$1,603–2,529

  2. Fly to São Paulo–Congonhas Airport, bus

    cheapest
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Congonhas Airport (CGH)plane plane GYE - CGH
    2. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    13h 43m
    R$1,545–4,550

  3. Bus via Porto Velho

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Plaza Nortebus bus
    2. Take the bus from Lima Plaza Norte to Cuscobus bus
    3. Take the bus from Cusco to Porto Velhobus bus
    4. Take the bus from Rodoviária de Porto Velho to Terminal Rodoviário de Santo Andrébus bus
    5d
    R$2,917–4,302

  4. Drive  5,820.2 km

    1. Drive from Guayaquil to Santa Isabelcar car 5,820.2 km
    3d 7h
    R$2,918–4,214

  5. Fly to Sao Jose Dos Campos, taxi

    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Sao Jose Dos Campos (SJK)plane plane GYE - SJK
    2. Take the taxi from Sao Jose Dos Campos (SJK) to Santa Isabeltaxi taxi
    13h 38m
    R$3,076–7,955

  6. Bus

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    2. Take the bus from Lima Javier Prado to Icabus bus
    3. Take the bus from Ica to Tietê Bus Terminalbus bus
    4. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 18h
    R$1,613–3,614

  7. Bus #2

    1. Take the bus from Terminal Terrestre de Guayaquil to Tumbesbus bus
    2. Take the bus from Tumbes to Lima Paseo de la Repúblicabus bus
    3. Take the bus from Lima - Atocongo to Tietê Bus Terminalbus bus
    4. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Rua Sebastião Claudiano, 12-78 - Recanto Imperial, Santa Isabel - SP, 07500-000, República Federativa do Brasil - Recanto Imperial, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 20h
    R$1,667–3,620

José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) flights

Calendar51Weekly Planes
Duration11h 10mAverage Duration
TicketR$1,117Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guayaquil to Santa Isabel.ExpandLaunch map view
  • Distance: 4,353 km
  • Duration: 10h 15m

What companies run services between Guayaquil, Ecuador and Santa Isabel, Brazil?

LATAM Chile, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) every 4 hours. Alternatively, you can take a bus from Terminal Terrestre de Guayaquil to Santa Isabel via Lima Plaza Norte, Cusco, Cusco, Rodoviária de Porto Velho, Terminal Rodoviário de Santo André, Prefeito Saladino, Brás, and Jardim Romano in around 5d.

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