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How to get fromGuayaquil to Santa Isabelby plane, bus, car, or taxi

Find Transport to Santa Isabel

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There are 7 ways to get from Guayaquil to Santa Isabel by plane, bus, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to São Paulo–Guarulhos International Airport

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU)plane plane GYE - GRU
    10h 15m
    R$1,749–2,750

  2. Bus

    cheapest
    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    2. Take the bus from Lima Javier Prado to Icabus bus
    3. Take the bus from Ica to Tietê Bus Terminalbus bus
    4. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 18h
    R$1,637–3,865

  3. Bus via Porto Velho

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Plaza Nortebus bus
    2. Take the bus from Lima Plaza Norte to Cuscobus bus
    3. Take the bus from Cusco to Porto Velhobus bus
    4. Take the bus from Rodoviária de Porto Velho to Terminal Rodoviario de Jundiaibus bus
    5. Take the bus from Terminal Rodoviario de Jundiai to Tietê Bus Terminalbus bus
    6. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d
    R$2,597–3,781

  4. Drive  5,820.2 km

    1. Drive from Guayaquil to Santa Isabelcar car 5,820.2 km
    3d 7h
    R$3,177–4,589

  5. Fly to São Paulo–Congonhas Airport, bus

    1. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Congonhas Airport (CGH)plane plane GYE - CGH
    2. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    13h 43m
    R$1,681–4,954

  6. Fly to Sao Jose Dos Campos, taxi

    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Sao Jose Dos Campos (SJK)plane plane GYE - SJK
    2. Take the taxi from Sao Jose Dos Campos (SJK) to Santa Isabeltaxi taxi
    13h 38m
    R$3,320–8,665

  7. Bus #2

    1. Take the bus from Terminal Terrestre de Guayaquil to Tumbesbus bus
    2. Take the bus from Tumbes to Lima Paseo de la Repúblicabus bus
    3. Take the bus from Lima - Atocongo to Tietê Bus Terminalbus bus
    4. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Rua Sebastião Claudiano, 12-78 - Recanto Imperial, Santa Isabel - SP, 07500-000, República Federativa do Brasil - Recanto Imperial, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 20h
    R$1,701–3,959

José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) flights

Calendar56Weekly Planes
Duration10h 47mAverage Duration
TicketR$1,217Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guayaquil to Santa Isabel.ExpandLaunch map view
  • Distance: 4,353 km
  • Duration: 10h 15m

What companies run services between Guayaquil, Ecuador and Santa Isabel, Brazil?

LATAM Chile, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) every 4 hours. Alternatively, you can take a bus from Terminal Terrestre de Guayaquil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasil via Lima Plaza Norte, Cusco, Cusco, Rodoviária de Porto Velho, Terminal Rodoviario de Jundiai, Tietê Bus Terminal, and Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil in around 5d.

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