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How to get fromGuayaquil to Santa Isabelby plane, bus, or car

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There are 7 ways to get from Guayaquil to Santa Isabel by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to São Paulo–Guarulhos International Airport

    best
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU)plane plane GYE - GRU
    9h 40m
    R$1,658–2,352

  2. Fly to São Paulo–Congonhas Airport, bus

    cheapest
    1. Fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Congonhas Airport (CGH)plane plane GYE - CGH
    2. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    12h 58m
    R$1,532–4,585

  3. Bus via Santa Cruz de la Sierra

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    2. Take the bus from Lima - Terminal Arriola to La Pazbus bus
    3. Take the bus from La Paz to Santa Cruzbus bus
    4. Take the bus from Santa Cruz to Terminal Barra Fundabus bus
    5. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    4d 18h
    R$2,076–5,006

  4. Drive 5,820.1 km

    1. Drive from Guayaquil to Santa Isabelcar car 5,820.1 km
    3d 7h
    R$2,999–4,331

  5. Bus

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    2. Take the bus from Lima Javier Prado to Icabus bus
    3. Take the bus from Ica to Porto Velhobus bus
    4. Take the bus from Rodoviária de Porto Velho to Terminal Rodoviário de Santo Andrébus bus
    5d
    R$3,481–5,519

  6. Bus #2

    1. Take the bus from Terminal Terrestre de Guayaquil to Lima Javier Pradobus bus
    2. Take the bus from Lima Javier Prado to Icabus bus
    3. Take the bus from Ica to Tietê Bus Terminalbus bus
    4. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasilbus bus
    5d 12h
    R$1,632–4,922

  7. Bus #3

    1. Take the bus from Guayaquil to Máncorabus bus
    2. Take the bus from Máncora to Gran Terminal Terrestre Plaza Nortebus bus
    3. Take the bus from Lima - Atocongo to Tietê Bus Terminalbus bus
    4. Take the bus from Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil to Rua Sebastião Claudiano, 12-78 - Recanto Imperial, Santa Isabel - SP, 07500-000, República Federativa do Brasil - Recanto Imperial, Santa Isabel - SP, 07500-000, Brasilbus bus
    6d 7h
    R$1,827–5,134

José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) flights

Calendar72Weekly Planes
Duration10h 9mAverage Duration
TicketR$1,205Cheapest Price
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Questions & Answers

Map of how to get from Guayaquil to Santa Isabel.ExpandLaunch map view
  • Distance: 4,353 km
  • Duration: 9h 40m

What companies run services between Guayaquil, Ecuador and Santa Isabel, Brazil?

LATAM Chile, Avianca - Aerovías del Continente Americano S.A., and Copa Airlines fly from José Joaquín De Olmedo International Airport (GYE) to São Paulo–Guarulhos International Airport (GRU) every 3 hours. Alternatively, you can take a bus from Terminal Terrestre de Guayaquil to Av. Cel. Bertoldo, 421 - Parque Sao Benedito, Santa Isabel - SP, 07500-000, Brasil via Lima Javier Prado, Lima - Terminal Arriola, La Paz, Santa Cruz, Terminal Barra Funda, Av. Mário De Andrade, 0, R. Pedro Vicente, 196, and Rua Guaporé, 117 - Ponto Final das Linhas 219 e 820 - Luz, São Paulo - SP, 01109-030, Brasil in around 4d 18h.

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