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How to get fromGuayaquil to Santo Domingo, Ecuadorby bus, car, or plane

Find Transport to Santo Domingo, Ecuador

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There are 4 ways to get from Guayaquil to Santo Domingo, Ecuador by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Terminal Terrestre de Guayaquil to Santo Domingo de los Coloradosbus bus Guayaquil / ...
    4h 52m
    $6–19

  2. Drive 274.5 km

    1. Drive from Guayaquil to Santo Domingo, Ecuadorcar car 274.5 km
    4h 13m
    $16–23

  3. Fly, bus

    1. Fly from José Joaquín De Olmedo International Airport (GYE) to Mariscal Sucre International Airport (UIO)plane plane GYE - UIO
    2. Take the bus from Quito Terminal Carcelén to Santo Domingo de los Coloradosbus bus
    4h 30m
    $93–161

  4. Bus via Santo Domingo de los Colorados

    1. Take the bus from Terminal Terrestre de Guayaquil to Santo Domingo de los Coloradosbus bus Santo Domingo / ...
    6h 51m
    $10–21

José Joaquín De Olmedo International Airport (GYE) to Mariscal Sucre International Airport (UIO) flights

Calendar104Weekly Planes
Duration53 minAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Guayaquil to Santo Domingo, Ecuador.ExpandLaunch map view
  • Distance: 266.9 km
  • Duration: 4h 52m

What companies run services between Guayaquil, Ecuador and Santo Domingo, Ecuador?

Trans Esmeraldas S.A. operates a bus from Terminal Terrestre de Guayaquil to Santo Domingo de los Colorados every 30 minutes. Tickets cost $11–19 and the journey takes 4h 52m. Two other operators also service this route.

Airlines
Bus operators

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