There are 7 ways to get from Guaymas to San Diego by bus, plane, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Hermosillo International Airport, fly to Tijuana International Airport
best- Take the bus from Guaymas to Hermosillobus
- Fly from Hermosillo International Airport (HMO) to Tijuana International Airport (TIJ)plane HMO - TIJ
7h 19m$109–279Bus #2
cheapest- Take the bus from Empalme to Tecatebus
- Take the bus from Sr 188 & Tecate Mart to El Cajon Transit Centerbus 894
19h 29m$75–182Bus via Mexicali
- Take the bus from Guaymas to Mexicali Centro Cívicobus Plus
- Take the bus from Mexicali to Tijuanabus
17h 45m$89–136Drive 637.1 mi
- Drive from Guaymas to San Diegocar 637.1 mi
12h 20m$117–168Bus to Ciudad Obregón International Airport, fly to Tijuana International Airport
- Take the bus from Guaymas to Ciudad Obregónbus
- Fly from Ciudad Obregón International Airport (CEN) to Tijuana International Airport (TIJ)plane CEN - TIJ
7h 42m$116–270Bus to Hermosillo International Airport, fly to San Diego International Airport
- Take the bus from Guaymas to Hermosillobus
- Fly from Hermosillo International Airport (HMO) to San Diego International Airport (SAN)plane HMO - SAN
10h 9m$101–466Bus
- Take the bus from Guaymas to Tijuanabus
19h 2m$84–204
Guaymas to San Diego by bus, foot, and tram
Questions & Answers
The cheapest way to get from Guaymas to San Diego is to bus via Mexicali which costs $85 - $140 and takes 17h 45m.
The fastest way to get from Guaymas to San Diego is to bus and fly which takes 7h 19m and costs $100 - $280.
No, there is no direct bus from Guaymas to San Diego. However, there are services departing from Guaymas and arriving at Broadway & 4th Av via Mexicali and San Ysidro Transit Center. The journey, including transfers, takes approximately 17h 45m.
The distance between Guaymas and San Diego is 540 miles. The road distance is 640.9 miles.
The best way to get from Guaymas to San Diego without a car is to bus via Mexicali which takes 17h 45m and costs $85 - $140.
It takes approximately 7h 19m to get from Guaymas to San Diego, including transfers.
Guaymas to San Diego bus services, operated by Tufesa Mexico, depart from Guaymas station.
Guaymas to San Diego bus services, operated by Tufesa Mexico, arrive at Mexicali Centro Cívico station.
Yes, the driving distance between Guaymas to San Diego is 641 miles. It takes approximately 12h 20m to drive from Guaymas to San Diego.
There are 2308+ hotels available in San Diego.
What companies run services between Guaymas, Mexico and San Diego, CA, USA?
You can take a bus from Guaymas to Broadway & 4th Av via Mexicali Centro Cívico, Mexicali, Tijuana, and San Ysidro Transit Center in around 17h 45m.
- Website
- volaris.com
Flights from Hermosillo International Airport to Tijuana International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $85–210
Flights from Ciudad Obregón International Airport to Tijuana International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $100–200
- Website
- aa.com
Flights from Hermosillo International Airport to San Diego International Airport via Phoenix
- Ave. Duration
- 7h 39m
- When
- Every day
- Estimated price
- $80–430
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Guaymas to Hermosillo
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- $11–25
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $11–25
- Titanium
- $12–25
Bus from Guaymas to Mexicali Centro Cívico
- Ave. Duration
- 12h 40m
- Frequency
- Twice daily
- Estimated price
- $65–95
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $65–95
- Titanium
- $70–85
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Every 3 hours
- Estimated price
- $10–24
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $10–24
- Titanium
- $11–24
Bus from Guaymas to Hermosillo
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- $11–25
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $11–25
- Titanium
- $12–25
Bus from Guaymas to Tijuana
- Ave. Duration
- 15h 10m
- Frequency
- Twice daily
- Estimated price
- $80–110
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $80–110
- Titanium
- $85–95
- Phone
- +52 664 104 7400
- [email protected]
- Website
- abc.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $20–40
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $15–40
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Guaymas to Tijuana
- Ave. Duration
- 15h 59m
- Frequency
- 5 times a day
- Estimated price
- $90–180
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobusesaguacaliente.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $9–15
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $14–35
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Empalme to Tecate
- Ave. Duration
- 15h
- Frequency
- Once daily
- Estimated price
- $70–140
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $14–35
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- futura.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $14–35
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 800 624 6618
- [email protected]
- Website
- albatrosautobuses.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $8–12
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +1 619-557-4555
- Website
- sdmts.com
Bus from Sr 188 & Tecate Mart to El Cajon Transit Center
- Ave. Duration
- 1h 11m
- Frequency
- 3 times a day
- Estimated price
- $2–5
- Website
- https://www.sdmts.com
- Schedules at
- https://www.sdmts.com/getting-around/departures-and-schedules
- One Way - Adult/Youth
- $2–5
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide































