There are 6 ways to get from Guaymas to Santa Ana by bus, plane, bus (Flixbus), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Hermosillo International Airport, fly to John Wayne Airport Orange County
best- Take the bus from Guaymas to Hermosillobus
- Fly from Hermosillo International Airport (HMO) to John Wayne Airport Orange County (SNA)plane HMO - SNA
8h 6m$139–561Bus
cheapest- Take the bus from Guaymas to Huntington Parkbus
- Take the bus from Huntington Park, CA - 2470 E Florence Ave to Santa Anabus El Paso
20h 40m$110–184Drive 717.7 mi
- Drive from Guaymas to Santa Anacar 717.7 mi
13h 47m$131–190Bus to Hermosillo International Airport, fly to Tijuana International Airport, train
- Take the bus from Guaymas to Hermosillobus
- Fly from Hermosillo International Airport (HMO) to Tijuana International Airport (TIJ)plane HMO - TIJ
- Take the train from San Diego to Santa Anatrain
10h 18m$138–444Bus to Ciudad Obregón International Airport, fly to Tijuana International Airport, train
- Take the bus from Guaymas to Ciudad Obregónbus
- Fly from Ciudad Obregón International Airport (CEN) to Tijuana International Airport (TIJ)plane CEN - TIJ
- Take the train from San Diego to Santa Anatrain
10h 40m$146–335Bus via Ensenada
- Take the bus from Empalme to Ensenadabus
- Take the bus from Ensenada to Tijuana International Airportbus
- Take the bus from Cross Border Xpress to Santa Anabus 2 / ...
24h 58m$115–202
Guaymas to Santa Ana by bus
Questions & Answers
The cheapest way to get from Guaymas to Santa Ana is to bus which costs $110 - $190 and takes 20h 40m.
The fastest way to get from Guaymas to Santa Ana is to bus and fly which takes 8h 6m and costs $130 - $600.
No, there is no direct bus from Guaymas to Santa Ana. However, there are services departing from Guaymas and arriving at Santa Ana via Huntington Park, CA - 2470 E Florence Ave. The journey, including transfers, takes approximately 20h 40m.
The distance between Guaymas and Santa Ana is 613 miles. The road distance is 721.9 miles.
The best way to get from Guaymas to Santa Ana without a car is to bus which takes 20h 40m and costs $110 - $190.
It takes approximately 8h 6m to get from Guaymas to Santa Ana, including transfers.
Guaymas to Santa Ana bus services, operated by Tufesa Mexico, depart from Guaymas station.
Guaymas to Santa Ana bus services, operated by Tufesa Mexico, arrive at Huntington Park station.
Yes, the driving distance between Guaymas to Santa Ana is 722 miles. It takes approximately 13h 47m to drive from Guaymas to Santa Ana.
There are 1629+ hotels available in Santa Ana.
What companies run services between Guaymas, Mexico and Santa Ana, CA, USA?
You can take a bus from Guaymas to Santa Ana via Huntington Park, CA - 2470 E Florence Ave in around 20h 40m.
- Website
- volaris.com
Flights from Hermosillo International Airport to Tijuana International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $85–310
Flights from Ciudad Obregón International Airport to Tijuana International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $100–200
- Website
- aa.com
Flights from Hermosillo International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $90–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Guaymas to Hermosillo
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- $10–25
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $10–25
- Titanium
- $12–25
Bus from Guaymas to Huntington Park
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $100–176
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $100–150
- Titanium
- $116–120
Bus from Guaymas to Hermosillo
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- $10–25
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $10–25
- Titanium
- $12–25
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Every 3 hours
- Estimated price
- $10–24
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $10–24
- Titanium
- $11–24
- [email protected]
- Website
- crossborderxpress.com
Bus from Huntington Park, CA - 2470 E Florence Ave to Santa Ana
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $17–25
- Schedules at
- crossborderxpress.com
Bus from Cross Border Xpress to Santa Ana
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $27–40
- Schedules at
- crossborderxpress.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Huntington Park, CA - 2470 E Florence Ave to Santa Ana
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- $4–8
- Schedules at
- flixbus.com
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $14–40
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobusesaguacaliente.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $9–14
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
Bus from Empalme to Ensenada
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- $75–110
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $14–35
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $14–35
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- futura.com.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $14–35
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 800 624 6618
- [email protected]
- Website
- albatrosautobuses.mx
Bus from Guaymas to Ciudad Obregón
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $8–12
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +52 664 104 7400
- [email protected]
- Website
- abc.com.mx
Bus from Ensenada to Tijuana International Airport
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- $12–25
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- +1 866 691 9732
- [email protected]
- Website
- eplalimo.com
Bus from Cross Border Xpress to Santa Ana
- Ave. Duration
- 2h 10m
- Frequency
- Every 3 hours
- Estimated price
- $30–45
- Website
- https://eplalimo.com/
- One Way
- $30–45
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