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How to get fromGuelph to Carlisleby train, plane, bus, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Guelph to Carlisle by train, plane, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Philadelphia International Airport

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Philadelphia International Airport (PHL)plane plane YYZ - PHL
    3. Take the train from 30th Street Station to Harrisburgtrain train
    10h 30m
    $645–2,088

  2. Drive 361.3 mi

    cheapest
    1. Drive from Guelph to Carlislecar car 361.3 mi
    8h 10m
    $83–120

  3. Train, bus

    1. Take the train from Guelph Central GO to Union Station GOtrain train Ki
    2. Take the bus from Toronto to Buffalobus bus
    3. Take the bus from Buffalo to DuBoisbus bus
    4. Take the bus from DuBois to State Collegebus bus
    5. Take the bus from State College Regional Airport to Harrisburg Bus Stationbus bus
    17h 54m
    $129–244

  4. Bus, train

    1. Take the bus from Guelph Central GO Bus to Aldershot GO Busbus bus 17
    2. Take the train from Aldershot to New York Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Harrisburgtrain train
    20h 33m
    $208–460

  5. Train, fly to Ronald Reagan Washington National Airport

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Ronald Reagan Washington National Airport (DCA)plane plane YYZ - DCA
    3. Take the train from Washington Union Station to 30th Street Stationtrain train
    4. Take the train from 30th Street Station to Harrisburgtrain train
    12h 10m
    $586–1,782

  6. Bus

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus 29
    2. Take the bus from Mississauga to Newarkbus bus
    3. Take the bus from Newark Penn Station to Harrisburg Bus Stationbus bus
    18h 58m
    $97–356

Guelph to Carlisle by train, bus, and foot

Calendar7Weekly Services
Duration17h 54mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

Map of how to get from Guelph to Carlisle.ExpandLaunch map view
  • Distance: 515.3 mi
  • Duration: 10h 30m

What companies run services between Guelph, ON, Canada and Carlisle, PA, USA?

You can take a bus from Guelph Central GO Bus to Hanover St & High St via Winston Churchill Transitway Station, Mississauga, Newark Penn Station, Harrisburg Bus Station, and Market Square Transfer Center in around 18h 58m.

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