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How to get fromGuelph to Des Moinesby train, plane, bus, car, shuttle, or bus (Flixbus, Greyhound)

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There are 10 ways to get from Guelph to Des Moines by train, plane, bus, car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly to Des Moines

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Des Moines (DSM)plane plane YYZ - DSM
    8h 18m
    $92–393

  2. Train to Toronto Pearson International Airport, fly to Fort Dodge Municipal Airport, drive

    cheapest
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Fort Dodge Municipal Airport (FOD)plane plane YYZ - FOD
    3. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    9h 57m
    $89–403

  3. Train, bus via Galesburg

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    21h 10m
    $326–649

  4. Train, bus

    1. Take the train from Guelph to Sarniatrain train
    2. Take the bus from Port Huron Station to Chicago Union Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    21h 13m

  5. Drive  780.2 mi

    1. Drive from Guelph to Des Moinescar car 780.2 mi
    13h 5m
    $161–232

  6. Train to Toronto Island Airport, fly to Des Moines

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Des Moines (DSM)plane plane YTZ - DSM
    8h 58m
    $97–427

  7. Train, bus to Buffalo Niagara International Airport, fly to Des Moines

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Take the bus from Toronto to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    11h 39m
    $126–518

  8. Bus, shuttle to Detroit, fly to Des Moines

    1. Take the bus from Kitchener to Londonbus bus
    2. Take a shuttle bus from Days Inn by Wyndham London to Detroit Airportshuttle bus
    3. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    10h 6m
    $172–869

  9. Train, bus #2

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    21h 13m
    $271–549

  10. Bus

    1. Take the bus from Guelph to Londonbus bus
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    23h 30m
    $143–229

Guelph to Des Moines by train, car, and bus

Calendar7Weekly Services
Duration21h 10mAverage Duration
Ticket$326Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guelph to Des Moines.ExpandLaunch map view
  • Distance: 773.6 mi
  • Duration: 8h 18m

What companies run services between Guelph, ON, Canada and Des Moines, IA, USA?

You can take a bus from Guelph to Des Moines via London, Detroit Bus Station, and Chicago Bus Station in around 23h 30m.

Airlines
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Bus operators

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