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How to get fromGuelph to Des Moinesby train, plane, bus, bus (Flixbus, Greyhound), car, or shuttle

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There are 9 ways to get from Guelph to Des Moines by train, plane, bus, bus (Flixbus, Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Des Moines (DSM)plane plane YYZ - DSM
    8h 2m
    $93–395

  2. Train, bus

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    18h 53m
    $166–452

  3. Bus

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to South Havenbus bus
    3. Take the bus from South Haven to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    23h 59m
    $133–223

  4. Drive  783.4 mi

    1. Drive from Guelph to Des Moinescar car 783.4 mi
    13h 7m
    $180–259

  5. Train to Toronto Island Airport, fly

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Des Moines (DSM)plane plane YTZ - DSM
    8h 13m
    $98–426

  6. Bus, bus to Buffalo Niagara International Airport, fly

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus
    2. Take the bus from Mississauga to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    10h 42m
    $132–542

  7. Train, shuttle to Detroit, fly

    1. Take the train from Guelph to Londontrain train
    2. Take a shuttle bus from London, ON - 105, Wharncliffe Road South, Manor Park to Detroit Airportshuttle bus
    3. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    10h 14m
    $162–750

  8. Train, bus via Galesburg

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    20h 45m
    $186–517

  9. Bus via Indianapolis

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit, MI to Indianapolis, INbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    24h 24m
    $132–244

Guelph to Des Moines by train, car, foot, and bus

Calendar7Weekly Services
Duration18h 53mAverage Duration
Ticket$166Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guelph to Des Moines.ExpandLaunch map view
  • Distance: 773.6 mi
  • Duration: 8h 2m

What companies run services between Guelph, ON, Canada and Des Moines, IA, USA?

You can take a bus from Guelph Central GO Bus to Des Moines via Victoria / Bingemans Centre Dr., Kitchener, Detroit Bus Station, South Haven, and Chicago Bus Station in around 23h 59m.

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