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How to get fromGuelph to Des Moinesby train, plane, bus, bus (Flixbus, Amtrak, Greyhound), car, shuttle, or bus (Flixbus, Greyhound)

Find Transport to Des Moines

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There are 10 ways to get from Guelph to Des Moines by train, plane, bus, bus (Flixbus, Amtrak, Greyhound), car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly to Des Moines

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Des Moines (DSM)plane plane YYZ - DSM
    8h 2m
    $93–395

  2. Train to Toronto Pearson International Airport, fly to Fort Dodge Municipal Airport, drive

    cheapest
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Fort Dodge Municipal Airport (FOD)plane plane YYZ - FOD
    3. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    9h 59m
    $91–397

  3. Train, bus

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    18h 53m
    $261–539

  4. Bus via Chicago

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit to East Lansingbus bus
    3. Take the bus from East Lansing Amtrak Station to Chicago Union Stationbus bus
    4. Take the bus from Chicago Bus Station to Des Moinesbus bus
    23h 34m

  5. Drive  780.2 mi

    1. Drive from Guelph to Des Moinescar car 780.2 mi
    13h 5m
    $179–258

  6. Train to Toronto Island Airport, fly to Des Moines

    1. Take the train from Guelph Central GO to Union Station GOtrain train
    2. Fly from Toronto Island Airport (YTZ) to Des Moines (DSM)plane plane YTZ - DSM
    8h 29m
    $98–426

  7. Bus, bus to Buffalo Niagara International Airport, fly to Des Moines

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus
    2. Take the bus from Mississauga to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Des Moines (DSM)plane plane BUF - DSM
    10h 40m
    $127–532

  8. Train, shuttle to Detroit, fly to Des Moines

    1. Take the train from Guelph to Londontrain train
    2. Take a shuttle bus from London, ON - 105, Wharncliffe Road South, Manor Park to Detroit Airportshuttle bus
    3. Fly from Detroit (DTW) to Des Moines (DSM)plane plane DTW - DSM
    10h 20m
    $167–827

  9. Train, bus via Galesburg

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    20h 45m
    $331–644

  10. Bus

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    24h 19m
    $145–249

Guelph to Des Moines by train, car, foot, and bus

Calendar7Weekly Services
Duration18h 53mAverage Duration
Ticket$261Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guelph to Des Moines.ExpandLaunch map view
  • Distance: 773.6 mi
  • Duration: 8h 2m

What companies run services between Guelph, ON, Canada and Des Moines, IA, USA?

You can take a bus from Guelph Central GO Bus to Des Moines via Victoria / Bingemans Centre Dr., Kitchener, Detroit, East Lansing, East Lansing Amtrak Station, Chicago Union Station, and Chicago Bus Station in around 23h 34m.

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Train operators
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