There are 10 ways to get from Guelph to Indianapolis by train, plane, bus, train (Amtrak), car, shuttle, bus (Flixbus), or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Toronto Pearson International Airport, fly
best- Take the train from Guelph Central GO to Bramalea GOtrain
- Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane YYZ - IND
6h 24m$423–1,115Bus
cheapest- Take the bus from Kitchener to Detroit Bus Stationbus FlixBus N2710
- Take the bus from Detroit, MI to Indianapolis, INbus Detroit
13h 27m$64–129Train, bus via Detroit
- Take the train from Guelph to Londontrain
- Take the train from London to Windsortrain
- Take the bus from Detroit, MI to Indianapolis, INbus
11h 48m$77–399Train
- Take the train from Guelph to Sarniatrain
- Take the train from Port Huron Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
17h 8m$196–520Drive 460.4 mi
- Drive from Guelph to Indianapoliscar 460.4 mi
8h 14m$106–153Train to Toronto Island Airport, fly
- Take the train from Guelph Central GO to Union Station GOtrain
- Fly from Toronto Island Airport (YTZ) to Indianapolis (IND)plane YTZ - IND
8h 50m$662–1,415Train to London International Airport, fly
- Take the train from Guelph to Londontrain
- Fly from London International Airport (YXU) to Indianapolis (IND)plane YXU - IND
11h 40m$202–1,265Train, shuttle to Buffalo Niagara International Airport, fly
- Take the train from Guelph Central GO to Bramalea GOtrain
- Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airport
- Fly from Buffalo Niagara International Airport (BUF) to Indianapolis (IND)plane BUF - IND
9h 35m$213–835Train, bus
- Take the train from Guelph to Londontrain
- Take the bus from London to Detroit Bus Stationbus
- Take the bus from Detroit, MI to Indianapolis, INbus
13h 27m$66–262Bus via Detroit
- Take the bus from Kitchener to Detroit Bus Stationbus FlixBus N2710
- Take the bus from Detroit Bus Station to Indianapolis Union Stationbus Greyhound US0112
13h 42m$77–139
Guelph to Indianapolis by train, car, and bus
Questions & Answers
The cheapest way to get from Guelph to Indianapolis is to bus which costs $60 - $130 and takes 13h 27m.
The fastest way to get from Guelph to Indianapolis is to train and fly which takes 6h 24m and costs $420 - $1,200.
No, there is no direct bus from Guelph to Indianapolis. However, there are services departing from Guelph Central GO Bus and arriving at Indianapolis, IN via Victoria / Bingemans Centre Dr., Kitchener and Detroit, MI. The journey, including transfers, takes approximately 13h 27m.
No, there is no direct train from Guelph to Indianapolis. However, there are services departing from Guelph and arriving at Indianapolis via Port Huron Station and Chicago Union Station. The journey, including transfers, takes approximately 17h 8m.
The distance between Guelph and Indianapolis is 497 miles. The road distance is 463.1 miles.
The best way to get from Guelph to Indianapolis without a car is to bus which takes 13h 27m and costs $60 - $130.
It takes approximately 6h 24m to get from Guelph to Indianapolis, including transfers.
Guelph to Indianapolis bus services, operated by Flixbus USA, depart from Kitchener station.
Guelph to Indianapolis train services, operated by VIA Rail, depart from Guelph station.
The best way to get from Guelph to Indianapolis is to train which takes 17h 8m and costs $190 - $550. Alternatively, you can bus, which costs $60 - $130 and takes 13h 27m.
What companies run services between Guelph, ON, Canada and Indianapolis, IN, USA?
You can take a train from Guelph to Indianapolis via Sarnia, Port Huron Station, and Chicago Union Station in around 17h 8m. Alternatively, you can take a bus from Guelph Central GO Bus to Indianapolis, IN via Victoria / Bingemans Centre Dr., Kitchener, and Detroit, MI in around 13h 27m.
- Website
- united.com
Flights from Toronto Pearson International Airport to Indianapolis
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–420
Flights from Toronto Pearson International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $85–470
Flights from Toronto Pearson International Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $100–550
Flights from Toronto Island Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $110–600
Flights from Toronto Island Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $95–1,400
Flights from Toronto Island Airport to Indianapolis via Newark
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $130–650
Flights from London International Airport to Indianapolis via Toronto Pearson International Airport
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $180–1,100
Flights from London International Airport to Indianapolis via Toronto Pearson International Airport, Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $220–1,200
Flights from London International Airport to Indianapolis via Toronto Pearson International Airport, Washington Dulles
- Ave. Duration
- 8h 34m
- When
- Every day
- Estimated price
- $260–1,300
Flights from Buffalo Niagara International Airport to Indianapolis via Washington Dulles
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $150–800
Flights from Buffalo Niagara International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $140–750
- Website
- aircanada.com
Flights from Toronto Pearson International Airport to Indianapolis
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–420
Flights from Toronto Pearson International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $85–470
Flights from Toronto Island Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $95–1,400
Flights from Toronto Island Airport to Indianapolis via Ottawa, Toronto Pearson International Airport
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $120–600
Flights from London International Airport to Indianapolis via Toronto Pearson International Airport
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $180–1,100
Flights from London International Airport to Indianapolis via Toronto Pearson International Airport, Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Buffalo Niagara International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $140–750
- Website
- delta.com
Flights from Toronto Pearson International Airport to Indianapolis via Detroit
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $70–420
Flights from Toronto Island Airport to Indianapolis via New York La Guardia
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $130–650
Flights from Buffalo Niagara International Airport to Indianapolis via Detroit
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $110–700
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 42m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–750
Flights from Buffalo Niagara International Airport to Indianapolis via Baltimore
- Ave. Duration
- 5h 41m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $160–850
- Website
- aa.com
Flights from Toronto Pearson International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $85–470
Flights from Toronto Island Airport to Indianapolis via New York La Guardia
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $130–650
Flights from Toronto Island Airport to Indianapolis via Boston
- Ave. Duration
- 6h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–700
Flights from Buffalo Niagara International Airport to Indianapolis via Reagan Washington
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $160–850
Flights from Buffalo Niagara International Airport to Indianapolis via Chicago O'Hare
- Ave. Duration
- 5h 14m
- When
- Every day
- Estimated price
- $140–750
- Phone
- +1 888-438-6646
- Website
- gotransit.com
Train from Guelph Central GO to Bramalea GO
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $7–10
- Website
- https://www.gotransit.com/en
- Website
- https://www.gotransit.com/en/see-schedules
- Passenger
- $7–10
Train from Guelph Central GO to Union Station GO
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $10–14
- Website
- https://www.gotransit.com/en
- Website
- https://www.gotransit.com/en/see-schedules
- Passenger
- $10–14
Train from Guelph Central GO to Bramalea GO
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $7–10
- Website
- https://www.gotransit.com/en
- Website
- https://www.gotransit.com/en/see-schedules
- Passenger
- $7–10
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Guelph to London
- Ave. Duration
- 2h 22m
- Frequency
- Once daily
- Estimated price
- $19–160
- Website
- https://www.viarail.ca/en
- Escape
- $19–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $21–75
- Economy Plus
- $24–85
Train from London to Windsor
- Ave. Duration
- 1h 57m
- Frequency
- 4 times a day
- Estimated price
- $29–170
- Website
- https://www.viarail.ca/en
- Escape
- $29–85
- Business
- $60–160
- Business Plus
- $70–170
- Economy
- $30–95
- Economy Plus
- $35–100
Train from Guelph to Sarnia
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $35–180
- Website
- https://www.viarail.ca/en
- Escape
- $35–100
- Business
- $65–170
- Business Plus
- $75–180
- Economy
- $35–110
- Economy Plus
- $40–120
Train from Guelph to London
- Ave. Duration
- 2h 22m
- Frequency
- Once daily
- Estimated price
- $19–160
- Website
- https://www.viarail.ca/en
- Escape
- $19–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $21–75
- Economy Plus
- $24–85
Train from Guelph to London
- Ave. Duration
- 2h 22m
- Frequency
- Once daily
- Estimated price
- $19–160
- Website
- https://www.viarail.ca/en
- Escape
- $19–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $21–75
- Economy Plus
- $24–85
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Port Huron Station to Chicago Union Station
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $100–210
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Detroit, MI to Indianapolis, IN
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- https://baronsbus.com
Bus from Detroit, MI to Indianapolis, IN
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- https://baronsbus.com
Bus from Detroit, MI to Indianapolis, IN
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–70
- Website
- https://baronsbus.com
- Phone
- +1 905 374 8111
- [email protected]
- Website
- niagaraairbus.com
Shuttle from Pearson International Airport Terminal 1 to Buffalo Airport
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $90–120
- Website
- https://www.niagaraairbus.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Kitchener to Detroit Bus Station
- Ave. Duration
- 5h 20m
- Frequency
- 3 times a week
- Estimated price
- $30–50
- Schedules at
- flixbus.com
Bus from London to Detroit Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- 4 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Kitchener to Detroit Bus Station
- Ave. Duration
- 5h 20m
- Frequency
- 3 times a week
- Estimated price
- $30–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Detroit Bus Station to Indianapolis Union Station
- Ave. Duration
- 5h 35m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Guelph to Indianapolis bus services, operated by Flixbus USA, arrive at Detroit Bus Station.
Guelph to Indianapolis train services, operated by VIA Rail, arrive at Sarnia station.
Yes, the driving distance between Guelph to Indianapolis is 463 miles. It takes approximately 8h 14m to drive from Guelph to Indianapolis.
Book your Guelph to Indianapolis train tickets online with Omio.
There are 775+ hotels available in Indianapolis.



















