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How to get fromGuelph to Louisvilleby train, plane, bus, car, shuttle, bus (Flixbus, Amtrak), or bus (Flixbus, Greyhound, Amtrak)

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There are 12 ways to get from Guelph to Louisville by train, plane, bus, car, shuttle, bus (Flixbus, Amtrak), or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly to Louisville International Airport

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane plane YYZ - SDF
    8h 47m
    $101–565

  2. Bus

    cheapest
    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 24m
    $86–169

  3. Train, bus

    1. Take the train from Guelph to Londontrain train
    2. Take the train from London to Windsortrain train
    3. Take the bus from Detroit to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    14h 43m
    $97–441

  4. Train, bus via Chicago

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    20h 3m
    $328–662

  5. Drive  539.8 mi

    1. Drive from Guelph to Louisvillecar car 539.8 mi
    9h 12m
    $124–179

  6. Bus, bus to Buffalo Niagara International Airport, fly to Louisville International Airport

    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus
    2. Take the bus from Mississauga to Buffalobus bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Louisville International Airport (SDF)plane plane BUF - SDF
    11h 24m
    $140–772

  7. Train, shuttle to Detroit, fly to Louisville International Airport

    1. Take the train from Guelph to Londontrain train
    2. Take a shuttle bus from London, ON - 105, Wharncliffe Road South, Manor Park to Detroit Airportshuttle bus
    3. Fly from Detroit (DTW) to Louisville International Airport (SDF)plane plane DTW - SDF
    10h 48m
    $175–1,000

  8. Train, shuttle to Detroit, fly to Blue Grass Airport, drive

    1. Take the train from Guelph to Londontrain train
    2. Take a shuttle bus from London, ON - 105, Wharncliffe Road South, Manor Park to Detroit Airportshuttle bus
    3. Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane plane DTW - LEX
    4. Drive from Lexington-Airport-LEX to Louisvillecar car
    10h 54m
    $142–696

  9. Train to Toronto Pearson International Airport, fly to Indianapolis, bus

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    9h 32m
    $112–511

  10. Train to Toronto Pearson International Airport, fly to Nashville, bus

    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Nashville (BNA)plane plane YYZ - BNA
    3. Take the bus from Nashville to Louisville, KYbus bus
    10h 59m
    $152–1,464

  11. Bus via Detroit

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 39m
    $104–174

  12. Train, bus #2

    1. Take the train from Guelph to Londontrain train
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 52m
    $105–303

Guelph to Louisville by train, car, and bus

Calendar7Weekly Services
Duration14h 43mAverage Duration
Ticket$97Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guelph to Louisville.ExpandLaunch map view
  • Distance: 541.3 mi
  • Duration: 8h 47m

What companies run services between Guelph, ON, Canada and Louisville, KY, USA?

You can take a bus from Guelph Central GO Bus to Louisville, KY via Victoria / Bingemans Centre Dr., Kitchener, Detroit, and Indianapolis Union Station in around 16h 24m.

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