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How to get fromGuelph to Louisvilleby train, plane, bus, car, bus (Flixbus, Amtrak), or bus (Flixbus, Greyhound, Amtrak)

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There are 8 ways to get from Guelph to Louisville by train, plane, bus, car, bus (Flixbus, Amtrak), or bus (Flixbus, Greyhound, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Louisville International Airport (SDF)plane plane YYZ - SDF
    6h 21m
    $110–663

  2. Bus via London

    cheapest
    1. Take the bus from Guelph to Londonbus bus
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 15m
    $82–164

  3. Bus, train

    1. Take the bus from Guelph Central GO Bus to Aldershot GO Busbus bus 17
    2. Take the train from Aldershot to Windsortrain train
    3. Take the bus from Detroit to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    15h 5m
    $106–324

  4. Train, bus via Chicago

    1. Take the train from Guelph to Sarniatrain train
    2. Take the train from Port Huron Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    20h 28m
    $328–664

  5. Drive  539.8 mi

    1. Drive from Guelph to Louisvillecar car 539.8 mi
    9h 12m
    $111–161

  6. Train to London International Airport, fly

    1. Take the train from Guelph to Londontrain train
    2. Fly from London International Airport (YXU) to Louisville International Airport (SDF)plane plane YXU - SDF
    12h 55m
    $261–1,565

  7. Bus

    1. Take the bus from Kitchener to Detroit Bus Stationbus bus
    2. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    16h 39m
    $108–184

  8. Train, bus

    1. Take the train from Guelph to Londontrain train
    2. Take the bus from London to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    17h 17m
    $112–311

Guelph to Louisville by bus, train, and car

Calendar7Weekly Services
Duration15h 5mAverage Duration
Ticket$106Cheapest Price
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Comparing Your Travel Options

Map of how to get from Guelph to Louisville.ExpandLaunch map view
  • Distance: 541.3 mi
  • Duration: 6h 21m

What companies run services between Guelph, ON, Canada and Louisville, KY, USA?

You can take a bus from Guelph to Louisville, KY via London, Detroit, and Indianapolis Union Station in around 16h 15m.

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