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How to get fromGuelph to Pittsburghby train, plane, bus, bus (Greyhound), car, or bus (Flixbus)

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There are 7 ways to get from Guelph to Pittsburgh by train, plane, bus, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Toronto Pearson International Airport, fly, bus

    best
    1. Take the train from Guelph Central GO to Bramalea GOtrain train
    2. Fly from Toronto Pearson International Airport (YYZ) to Pittsburgh International Airport (PIT)plane plane YYZ - PIT
    3. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    6h 21m

  2. Bus via Youngstown

    cheapest
    1. Take the bus from Guelph Central GO Bus to Winston Churchill Transitway Stationbus bus 29
    2. Take the bus from Mississauga to Buffalobus bus
    3. Take the bus from Buffalo, NY to Youngstown, OHbus bus
    4. Take the bus from Youngstown Bus Stop to Pittsburgh Intermodal Stationbus bus
    11h 4m
    $55–139

  3. Bus, train

    1. Take the bus from Guelph Central GO Bus to Aldershot GO Busbus bus 17
    2. Take the train from Aldershot to Buffalotrain train
    3. Take the train from Buffalo Depew Station to Cleveland Amtraktrain train
    4. Take the train from Cleveland Amtrak to Pittsburgh Amtrak Stationtrain train
    13h 52m
    $134–388

  4. Drive 308.7 mi

    1. Drive from Guelph to Pittsburghcar car 308.7 mi
    5h 38m
    $71–103

  5. Train to London International Airport, fly

    1. Take the train from Guelph to Londontrain train
    2. Fly from London International Airport (YXU) to Pittsburgh International Airport (PIT)plane plane YXU - PIT
    11h 57m
    $570–1,963

  6. Train, bus

    1. Take the train from Guelph Central GO to Union Station GOtrain train Ki
    2. Take the bus from Toronto to Buffalobus bus
    3. Take the bus from Buffalo to Pittsburghbus bus
    13h 45m
    $125–233

  7. Bus

    1. Take the bus from Guelph Central GO Bus to Renforth Transitway Stationbus bus 29
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    3. Take the bus from Buffalo to Pittsburghbus bus
    14h 47m
    $128–230

Guelph to Pittsburgh by bus

Calendar7Weekly Buses
Duration11h 4mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from Guelph to Pittsburgh.ExpandLaunch map view
  • Distance: 287 mi
  • Duration: 6h 21m

What companies run services between Guelph, ON, Canada and Pittsburgh, PA, USA?

You can take a bus from Guelph Central GO Bus to Pittsburgh Intermodal Station via Winston Churchill Transitway Station, Mississauga, Buffalo, NY, Youngstown, OH, and Youngstown Bus Stop in around 11h 4m.

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