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How to get fromHamilton to Mayo Clinicby bus, plane, train, bus (Flixbus), car, or shuttle

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There are 10 ways to get from Hamilton to Mayo Clinic by bus, plane, train, bus (Flixbus), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Toronto Pearson International Airport, fly to Rochester

    best
    1. Take the bus from King St. W. @ Summers Ln. to Pearson International Airport Terminal 1bus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Rochester (RST)plane plane YYZ - RST
    9h 11m
    $74–400

  2. Train, bus via Detroit

    1. Take the train from Aldershot to Windsortrain train
    2. Take the train from Detroit to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    20h 26m
    $242–558

  3. Bus

    1. Take the bus from Hamilton GO Centre Bus to Square Onebus bus 40 / ...
    2. Take the bus from Mississauga to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    23h 34m
    $172–273

  4. Drive 821.5 mi

    1. Drive from Hamilton to Mayo Cliniccar car 821.5 mi
    13h 38m
    $188–272

  5. Bus to Toronto Pearson International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from King St. W. @ Summers Ln. to Pearson International Airport Terminal 1bus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Minneapolis–Saint Paul International Airport (MSP)plane plane YYZ - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 20m
    $360–1,162

  6. Bus, shuttle to Buffalo Niagara International Airport, fly to Rochester

    1. Take the bus from King St. W. @ Summers Ln. to Pearson International Airport Terminal 1bus bus
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Rochester (RST)plane plane BUF - RST
    9h 56m
    $199–720

  7. Bus, shuttle to Buffalo Niagara International Airport, fly to Minneapolis–Saint Paul International Airport

    1. Take the bus from King St. W. @ Summers Ln. to Pearson International Airport Terminal 1bus bus
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    3. Fly from Buffalo Niagara International Airport (BUF) to Minneapolis–Saint Paul International Airport (MSP)plane plane BUF - MSP
    4. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 56m
    $270–832

  8. Bus via Kitchener

    1. Take the bus from Hamilton GO Centre Bus to Victoria St. N. @ Bingemans Centre Dr.bus bus 17
    2. Take the bus from Kitchener to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    24h 9m
    $173–271

  9. Train, bus

    1. Take the train from Aldershot to Buffalotrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    26h 39m
    $271–655

  10. Train, bus #2

    1. Take the train from Aldershot to Buffalotrain train
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    27h 14m
    $354–835

Hamilton to Mayo Clinic by train, car, bus, and foot

Calendar7Weekly Services
Duration20h 26mAverage Duration
Ticket$242Cheapest Price
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Questions & Answers

Map of how to get from Hamilton to Mayo Clinic.ExpandLaunch map view
  • Distance: 692.2 mi
  • Duration: 9h 11m

What companies run services between Hamilton, ON, Canada and Mayo Clinic, MN, USA?

You can take a bus from Hamilton GO Centre Bus to Mayo Clinic via Square One, Mississauga, Detroit Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 23h 34m.

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