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How to get fromHampton Inn Buffalo-South/I-90, West Seneca to Bostonby bus, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

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There are 6 ways to get from Hampton Inn Buffalo-South/I-90, West Seneca to Boston by bus, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 42 bus to Buffalo Niagara International Airport, fly

    best
    1. Take the bus from Slade Avenue & Ridge Road to Ellicott Street & MTC Staticbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Boston Logan Airport (BOS)plane plane BUF - BOS
    3h 48m
    $77–450

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Buffalo to Bostonbus bus Greyhound US0171
    11h 39m
    $72–142

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Bostontrain train Lake Shore Limited
    11h 38m
    $180–355

  4. Drive 454.2 mi

    1. Drive from Hampton Inn Buffalo-South/I-90, West Seneca to Bostoncar car 454.2 mi
    7h 57m
    $83–120

  5. Bus to Rochester, fly

    1. Take the bus from Buffalo to Rochester Bus Stopbus bus
    2. Fly from Rochester (ROC) to Boston Logan Airport (BOS)plane plane ROC - BOS
    5h 10m
    $96–447

  6. Bus via Ithaca (Flixbus)

    1. Take the bus from Buffalo to Ithacabus bus FlixBus 2685 / ...
    2. Take the bus from Ithaca to Bostonbus bus FlixBus 2691
    14h 18m
    $88–147

Hampton Inn Buffalo-South/I-90, West Seneca to Boston by foot and bus (Greyhound)

Calendar14Weekly Services
Duration11h 39mAverage Duration
Ticket$72Cheapest Price
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Questions & Answers

Map of how to get from Hampton Inn Buffalo-South/I-90, West Seneca to Boston.ExpandLaunch map view
  • Distance: 414.1 mi
  • Duration: 3h 48m

What companies run services between Hampton Inn Buffalo-South/I-90, West Seneca, NY, USA and Boston, MA, USA?

Amtrak operates a train from Buffalo Depew Station to Boston once daily. Tickets cost $150–320 and the journey takes 11h 27m. Alternatively, Greyhound USA operates a bus from Buffalo to Boston twice daily. Tickets cost $70–140 and the journey takes 10h 5m.

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