What is the cheapest way to get from Hannibal to Des Moines?

The cheapest way to get from Hannibal to Des Moines is to drive which costs $40 - $60 and takes 4h 34m.

What is the fastest way to get from Hannibal to Des Moines?

The fastest way to get from Hannibal to Des Moines is to drive which takes 4h 34m and costs $40 - $60.

How far is it from Hannibal to Des Moines?

The distance between Hannibal and Des Moines is 376 miles. The road distance is 219.3 miles.

How do I travel from Hannibal to Des Moines without a car?

The best way to get from Hannibal to Des Moines without a car is to train and bus which takes 7h 48m and costs $130 - $220.

How long does it take to get from Hannibal to Des Moines?

It takes approximately 7h 48m to get from Hannibal to Des Moines, including transfers.

Can I drive from Hannibal to Des Moines?

Yes, the driving distance between Hannibal to Des Moines is 219 miles. It takes approximately 4h 34m to drive from Hannibal to Des Moines.

Where can I stay near Des Moines?

There are 251+ hotels available in Des Moines.

Hannibal to Des Moines - 5 ways to travel via train, bus, car, and shuttle

How to get fromHannibal to Des Moines

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There are 5 ways to get from Hannibal to Des Moines by train, bus, car, shuttle, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train, bus
best
1. Take the train from Quincy Amtrak Station to Galesburg Amtrak Stationtrain Illinois Zephyr / ...
2. Take the bus from Galesburg to Des Moinesbus Greyhound US0157S
7h 48m
$131–218
Drive 218 mi
cheapest
1. Drive from Hannibal to Des Moinescar 218 mi
4h 34m
$40–58
Shuttle to Lambert–St. Louis International Airport, fly
1. Take a shuttle bus from Hannibal to St. Louisshuttle
2. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane STL - DSM
7h 14m
$110–474
Shuttle to Columbia Regional Airport, fly
1. Take a shuttle bus from Hannibal to Columbiashuttle
2. Fly from Columbia Regional Airport (COU) to Des Moines (DSM)plane COU - DSM
7h 33m
$147–485
Taxi to Quincy Regional Airport, fly
1. Take the taxi from Hannibal to Quincy Regional Airport (UIN)taxi
2. Fly from Quincy Regional Airport (UIN) to Des Moines (DSM)plane UIN - DSM
5h 2m
$154–471

Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights

145Weekly Planes

4h 54mAverage Duration

$76Cheapest Price

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Questions & Answers

Map of how to get from Hannibal to Des Moines.

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Distance: 373.9 mi
Duration: 7h 48m

What companies run services between Hannibal, MO, USA and Des Moines, IA, USA?

There is no direct connection from Hannibal to Des Moines. However, you can take the taxi to Quincy Amtrak Station, take the train to Galesburg Amtrak Station, walk to Galesburg, then take the bus to Des Moines. Alternatively, you can drive from Hannibal to Des Moines in around 4h 34m.

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