There are 5 ways to get from Hannibal to Indiana by train, bus, train (Amtrak), car, shuttle, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Quincy Amtrak Station to Galesburg Amtrak Stationtrain Illinois Zephyr / ...
- Take the bus from Galesburg to Indianapolis Union Stationbus Greyhound US0157S
7h 43m$141–228Shuttle, bus
cheapest- Take a shuttle bus from Hannibal to St. LouisPalmyra
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus Greyhound US0421
8h 17m$53–83Train (Amtrak)
- Take the train from Quincy Amtrak Station to Chicago Union Stationtrain Carl Sandburg / ...
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
10h 45m$181–378Drive 305.2 mi
- Drive from Hannibal to Indianapoliscar 305.2 mi
5h 10m$56–81Shuttle, fly, train
- Take a shuttle bus from Hannibal to St. Louis
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
- Take the train from Museum Campus/11th St. to Gary Metro Centertrain
6h 13m$78–388
Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW) flights
Comparing Your Travel Options
The cheapest way to get from Hannibal to Indiana is to shuttle and bus which costs $50 - $85 and takes 8h 17m.
The fastest way to get from Hannibal to Indiana is to drive which takes 5h 10m and costs $55 - $85.
No, there is no direct train from Hannibal station to Indiana. However, there are services departing from Quincy Amtrak Station and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 10h 45m.
The distance between Hannibal and Indiana is 426 miles. The road distance is 307 miles.
The best way to get from Hannibal to Indiana without a car is to train and bus which takes 7h 43m and costs $140 - $230.
It takes approximately 7h 43m to get from Hannibal to Indiana, including transfers.
Hannibal to Indiana train services, operated by Amtrak, depart from Quincy Amtrak Station.
Indiana is 1h ahead of Hannibal. It is currently 4:16 PM in Hannibal and 5:16 PM in Indiana.
Hannibal to Indiana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Hannibal to Indiana is 307 miles. It takes approximately 5h 10m to drive from Hannibal to Indiana.
What companies run services between Hannibal, MO, USA and Indiana, USA?
You can take a vehicle from Hannibal to Indianapolis via Quincy Amtrak Station and Chicago Union Station in around 10h 45m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $50–350
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Quincy Amtrak Station to Galesburg Amtrak Station
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- $35–85
- Website
- Amtrak
Train from Quincy Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 21m
- Frequency
- Twice daily
- Estimated price
- $70–180
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $45–120
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Galesburg to Indianapolis Union Station
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
There are 875+ hotels available in Indiana.





