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How to get fromHannibal to Madisonby train, bus, car, shuttle, or plane

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There are 5 ways to get from Hannibal to Madison by train, bus, car, shuttle, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    9h 9m
    $161–313

  2. Drive  319.7 mi

    cheapest
    1. Drive from Hannibal to Madisoncar car 319.7 mi
    5h 57m
    $59–85

  3. Shuttle to Lambert–St. Louis International Airport, fly to General Mitchell International Airport, bus

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    3. Take the bus from Mitchell Airport to Madison, WI-Lake St.bus bus
    7h 25m
    $518–908

  4. Train, bus via Milwaukee

    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus bus
    9h 55m
    $175–348

  5. Train to Chicago O'Hare International Airport, fly to Dane County Regional Airport-Truax Field

    1. Take the train from Quincy Amtrak Station to La Grange Amtraktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Dane County Regional Airport-Truax Field (MSN)plane plane ORD - MSN
    8h 37m
    $192–658

Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) flights

Calendar16Weekly Planes
Duration1h 32mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hannibal to Madison.ExpandLaunch map view
  • Distance: 482.5 mi
  • Duration: 9h 9m

What companies run services between Hannibal, MO, USA and Madison, WI, USA?

There is no direct connection from Hannibal to Madison. However, you can take the taxi to Quincy Amtrak Station, take the train to Chicago Union Station, walk to W Jackson Blvd, after S Clinton St, then take the bus to 250 N. Lake St - Madison UW Campus. Alternatively, you can drive from Hannibal to Madison in around 5h 57m.

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