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How to get fromHannibal to Niagara Fallsby shuttle, plane, train (Amtrak), bus, car, or train

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There are 8 ways to get from Hannibal to Niagara Falls by shuttle, plane, train (Amtrak), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Lambert–St. Louis International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    9h 34m
    $131–678

  2. Shuttle to Lambert–St. Louis International Airport, fly to Toronto Pearson International Airport, bus

    cheapest
    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)plane plane STL - YYZ
    3. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    8h 45m
    $101–497

  3. Train

    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    3. Take the train from Buffalo Depew Station to Niagara Falls Amtrak Stationtrain train
    18h 15m
    $269–708

  4. Shuttle, bus

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Take the bus from St Louis Bus Station to Columbusbus bus
    3. Take the bus from Columbus - Mound St to Buffalo, NYbus bus
    24h 38m
    $118–213

  5. Drive  783.3 mi

    1. Drive from Hannibal to Niagara Fallscar car 783.3 mi
    13h 21m
    $143–207

  6. Train to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Quincy Amtrak Station to La Grange Amtraktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    10h 58m
    $313–561

  7. Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    10h 55m
    $306–578

  8. Shuttle, bus via Pittsburgh

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    28h 26m
    $160–365

Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF) flights

Calendar103Weekly Planes
Duration4h 49mAverage Duration
Ticket$118Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hannibal to Niagara Falls.ExpandLaunch map view
  • Distance: 822.1 mi
  • Duration: 9h 34m

What companies run services between Hannibal, MO, USA and Niagara Falls, NY, USA?

You can take a vehicle from Hannibal to Niagara Falls Amtrak Station via Quincy Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 18h 15m.

Airlines
Train operators
Bus operators

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