There are 4 ways to get from Hannibal to Omaha by bus (Greyhound), car, shuttle, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from Quincy Public Transit Hub to Des Moinesbus Greyhound US0153S
- Take the bus from Des Moines to Omaha, NEbus Greyhound US0123S
9h 36m$121–196Drive 322.2 mi
cheapest- Drive from Hannibal to Omahacar 322.2 mi
5h 28m$59–85Shuttle to Lambert–St. Louis International Airport, fly
- Take a shuttle bus from Hannibal to St. Louis
- Fly from Lambert–St. Louis International Airport (STL) to Omaha (OMA)plane STL - OMA
5h 48m$636–944Shuttle to Columbia Regional Airport, fly
- Take a shuttle bus from Hannibal to Columbia
- Fly from Columbia Regional Airport (COU) to Omaha (OMA)plane COU - OMA
8h 43m$178–595
Lambert–St. Louis International Airport (STL) to Omaha (OMA) flights
Questions & Answers
The cheapest way to get from Hannibal to Omaha is to drive which costs $55 - $85 and takes 5h 28m.
The fastest way to get from Hannibal to Omaha is to drive which takes 5h 28m and costs $55 - $85.
No, there is no direct bus from Hannibal to Omaha. However, there are services departing from Quincy Public Transit Hub and arriving at Omaha, NE via Des Moines. The journey, including transfers, takes approximately 9h 36m.
The distance between Hannibal and Omaha is 438 miles. The road distance is 324.1 miles.
The best way to get from Hannibal to Omaha without a car is to bus which takes 9h 36m and costs $120 - $200.
It takes approximately 9h 36m to get from Hannibal to Omaha, including transfers.
Hannibal to Omaha bus services, operated by Greyhound USA, depart from Quincy Public Transit Hub station.
Hannibal to Omaha bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between Hannibal to Omaha is 324 miles. It takes approximately 5h 28m to drive from Hannibal to Omaha.
There are 290+ hotels available in Omaha.
What companies run services between Hannibal, MO, USA and Omaha, NE, USA?
You can take a vehicle from Hannibal to Omaha, NE via Quincy Public Transit Hub and Des Moines in around 9h 36m.
- Website
- united.com
Flights from Columbia Regional Airport to Omaha via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $95–490
Flights from Columbia Regional Airport to Omaha via Denver
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $130–600
- Website
- aa.com
Flights from Columbia Regional Airport to Omaha via Dallas/Ft.Worth
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $120–600
Flights from Columbia Regional Airport to Omaha via Chicago O'Hare
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $95–490
Flights from Columbia Regional Airport to Omaha via Charlotte
- Ave. Duration
- 9h 11m
- When
- Every day
- Estimated price
- $160–750
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Omaha
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $80–500
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Quincy Public Transit Hub to Des Moines
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Des Moines to Omaha, NE
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
- Phone
- +1-888-875-6287
- Website
- oatstransit.org
Shuttle from Hannibal to St. Louis
- Ave. Duration
- 1h 51m
- Frequency
- Twice a week
- Estimated price
- $4–7
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Shuttle from Hannibal to Columbia
- Ave. Duration
- 1h 45m
- Frequency
- Twice a week
- Estimated price
- $4–6
- Website
- https://www.oatstransit.org
- Schedules at
- https://www.oatstransit.org/schedules
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide


