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How to get fromHannibal to South Bendby train (Amtrak), car, shuttle, plane, train, or bus

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There are 6 ways to get from Hannibal to South Bend by train (Amtrak), car, shuttle, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    2. Take the train from Chicago Union Station to South Bend Stationtrain train Lake Shore Limited / ...
    7h 20m
    $162–308

  2. Drive  356.4 mi

    cheapest
    1. Drive from Hannibal to South Bendcar car 356.4 mi
    6h 24m
    $65–94

  3. Shuttle to Lambert–St. Louis International Airport, fly to Chicago Midway International Airport, train

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    3. Take the train from Chicago Union Station to South Bend Stationtrain train
    7h 46m
    $94–431

  4. Train, bus (Amtrak)

    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    2. Take the bus from Chicago Union Station to South Bend Stationbus bus Amtrak Thruway Connecting Service
    7h 20m
    $163–293

  5. Shuttle to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport, train

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    3. Take the train from Chicago Union Station to South Bend Stationtrain train
    8h 5m
    $361–778

  6. Train to Chicago O'Hare International Airport, fly to South Bend

    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to South Bend (SBN)plane plane ORD - SBN
    8h 7m
    $203–651

Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW) flights

Calendar32Weekly Planes
Duration1h 5mAverage Duration
Ticket$51Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hannibal to South Bend.ExpandLaunch map view
  • Distance: 413 mi
  • Duration: 7h 20m

What companies run services between Hannibal, MO, USA and South Bend, IN, USA?

You can take a vehicle from Hannibal to South Bend Station via Quincy Amtrak Station and Chicago Union Station in around 7h 20m.

Airlines
Train operators
Bus operators

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