There are 10 ways to get from Harlem to Syracuse by bus (Greyhound), train (Amtrak), car, bus, plane, bus (Flixbus), or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Port Authority Bus Terminal to Syracuse Bus Stationbus Greyhound US0205 / ...
6h 28m$43–167Train
- Take the train from Yonkers Amtrak Station to Syracuse Regional Transportation Centertrain Maple Leaf / ...
6h 36m$82–241Drive 233 mi
- Drive from Harlem to Syracusecar 233 mi
5h 15m$43–62Bus to Laguardia Airport, fly to Syracuse Hancock International Airport
- Take the bus from W 125 St/Malcolm X Blvd to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
4h 36m$99–665Bus via New York Midtown (Flixbus)
- Take the bus from New York Midtown to Syracuse Bus Stationbus FlixBus 2685 / ...
6h 31m$48–83Train, train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport
- Take the train from 125th Street - Harlem to Grand Central Terminaltrain
- Take the train from Grand Central Terminal to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
5h$96–585Fly Laguardia Airport to Rochester, train
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 26m$137–849Fly Newark Liberty International Airport to Rochester, train
- Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane EWR - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 48m$532–1,823Fly Laguardia Airport to Buffalo Niagara International Airport, bus
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
- Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus
6h 34m$120–697Fly John F. Kennedy International Airport to Ithaca Tompkins Regional Airport, bus
- Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)plane JFK - ITH
- Take the bus from Ithaca to Syracuse Bus Stationbus
6h 51m$64–324
Harlem to Syracuse by bus and foot
Questions & Answers
The cheapest way to get from Harlem to Syracuse is to drive which costs $40 - $65 and takes 5h 15m.
The fastest way to get from Harlem to Syracuse is to bus and fly which takes 4h 36m and costs $95 - $700.
No, there is no direct bus from Harlem to Syracuse station. However, there are services departing from Malcolm X Blvd/W 125 St and arriving at Syracuse Bus Station via Port Authority Bus Terminal. The journey, including transfers, takes approximately 6h 28m.
No, there is no direct train from Harlem to Syracuse. However, there are services departing from 125th Street - Harlem and arriving at Syracuse Regional Transportation Center via Yonkers Amtrak Station. The journey, including transfers, takes approximately 6h 36m.
The distance between Harlem and Syracuse is 267 miles. The road distance is 234.3 miles.
The best way to get from Harlem to Syracuse without a car is to bus which takes 6h 28m and costs $40 - $170.
It takes approximately 6h 28m to get from Harlem to Syracuse, including transfers.
Harlem to Syracuse bus services, operated by Greyhound USA, depart from Port Authority Bus Terminal station.
Harlem to Syracuse train services, operated by Amtrak, depart from Yonkers Amtrak Station.
The best way to get from Harlem to Syracuse is to bus which takes 6h 28m and costs $40 - $170. Alternatively, you can train, which costs $80 - $250 and takes 6h 36m.
What companies run services between Harlem, NY, USA and Syracuse, NY, USA?
Greyhound USA operates a bus from Port Authority Bus Terminal to Syracuse Bus Station every 2 hours. Tickets cost $35–75 and the journey takes 4h 45m. Trailways also services this route 4 times a day. Alternatively, Amtrak operates a train from Yonkers Amtrak Station to Syracuse Regional Transportation Center twice daily. Tickets cost $85–190 and the journey takes 5h 13m. VIA Rail also services this route once daily.
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $95–650
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $75–550
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $95–650
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–600
Flights from John F. Kennedy International Airport to Ithaca Tompkins Regional Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $35–280
- Website
- united.com
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $130–750
Flights from Newark Liberty International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $75–500
Flights from Newark Liberty International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $100–600
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $90–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $75–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Yonkers Amtrak Station to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 13m
- Frequency
- Twice daily
- Estimated price
- $85–190
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Yonkers Amtrak Station to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 5m
- Frequency
- Once daily
- Estimated price
- $75–230
- Website
- VIA Rail
- Escape
- $75–180
- Business
- $110–220
- Business Plus
- $120–230
- Economy
- $80–190
- Economy Plus
- $90–190
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from 125th Street - Harlem to Grand Central Terminal
- Ave. Duration
- 12 min
- Frequency
- Every 10 minutes
- Estimated price
- $5–10
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $5–7
- Peak
- $8–10
- Phone
- +1-718-217-5477
- Website
- Long Island Rail Road
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $5–9
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $5–9
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 2 hours
- Estimated price
- $35–75
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Saver
- $40–150
- Flexible
- $70–160
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
- Phone
- 877-690-5116
- Website
- MTA
Bus from W 125 St/Malcolm X Blvd to Laguardia Rd/94 St
- Ave. Duration
- 29 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- MTA
- Schedules at
- MTA scheduled
- Website
- MTA: World Cup 2026
- Standard Fare
- $3–8
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Hourly
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 2 hours
- Estimated price
- $24–40
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 6 times a week
- Estimated price
- $9–17
- Schedules at
- Flixbus USA
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More Questions & Answers
Harlem to Syracuse bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Harlem to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Harlem to Syracuse is 234 miles. It takes approximately 5h 15m to drive from Harlem to Syracuse.
There are 95+ hotels available in Syracuse.




















