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How to get fromHarpers Ferry to Des Moinesby car, plane, train, or bus

Find Transport to Des Moines

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There are 6 ways to get from Harpers Ferry to Des Moines by car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to La Crosse, fly

    best
    1. Drive from Harpers Ferry to La-Crosse-Airport-LSEcar car
    2. Fly from La Crosse (LSE) to Des Moines (DSM)plane plane LSE - DSM
    5h 31m
    $127–636

  2. Drive 209.4 mi

    cheapest
    1. Drive from Harpers Ferry to Des Moinescar car 209.4 mi
    4h 23m
    $39–56

  3. Drive, train, bus

    1. Drive from Harpers Ferry to La Crosse Amtrak Stationcar car
    2. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Des Moinesbus bus
    10h 11m
    $115–189

  4. Drive, train to Minneapolis–Saint Paul International Airport, fly

    1. Drive from Harpers Ferry to La Crosse Amtrak Stationcar car
    2. Take the train from La Crosse Amtrak Station to St. Paul-Minneapolistrain train
    3. Fly from Minneapolis–Saint Paul International Airport (MSP) to Des Moines (DSM)plane plane MSP - DSM
    7h 21m
    $154–723

  5. Drive, bus

    1. Drive from Harpers Ferry to La Crossecar car
    2. Take the bus from La Crosse to St. Paulbus bus
    3. Take the bus from St. Paul to Des Moinesbus bus
    10h 40m
    $115–169

  6. Drive, bus via Des Moines

    1. Drive from Harpers Ferry to La Crossecar car
    2. Take the bus from La Crosse to St. Paulbus bus
    3. Take the bus from Saint Paul Union Depot to Des Moinesbus bus
    11h 15m
    $85–149

La Crosse (LSE) to Des Moines (DSM) flights

Calendar21Weekly Planes
Duration4h 9mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Harpers Ferry to Des Moines.ExpandLaunch map view
  • Distance: 264.2 mi
  • Duration: 5h 31m

What companies run services between Harpers Ferry, IA, USA and Des Moines, IA, USA?

There is no direct connection from Harpers Ferry to Des Moines. However, you can drive to La-Crosse-Airport-LSE airport, fly to Des Moines (DSM), then take the taxi to Des Moines. Alternatively, you can take a vehicle from Harpers Ferry to Des Moines via La Crosse Amtrak Station, St. Paul-Minneapolis, and St. Paul in around 10h 11m.

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