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How to get fromHarpers Ferry to Knoxvilleby train, plane, bus, car, or subway

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There are 9 ways to get from Harpers Ferry to Knoxville by train, plane, bus, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from HARPERS FERRY W VA MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS)plane plane DCA - TYS
    4h 57m
    $243–1,103

  2. Drive 453.9 mi

    cheapest
    1. Drive from Harpers Ferry to Knoxvillecar car 453.9 mi
    7h 32m
    $83–120

  3. Train, bus

    1. Take the train from HARPERS FERRY W VA MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    18h 38m
    $226–349

  4. Train, subway to Washington Dulles International Airport, fly to Mcghee Tyson Airport

    1. Take the train from HARPERS FERRY W VA MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Mcghee Tyson Airport (TYS)plane plane IAD - TYS
    5h 15m
    $172–702

  5. Train, train to Baltimore-Washington International Airport, fly to Mcghee Tyson Airport

    1. Take the train from HARPERS FERRY W VA MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Mcghee Tyson Airport (TYS)plane plane BWI - TYS
    5h 33m
    $195–1,356

  6. Train to Ronald Reagan Washington National Airport, fly to Asheville Regional Airport, drive

    1. Take the train from HARPERS FERRY W VA MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Asheville Regional Airport (AVL)plane plane DCA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 37m
    $130–618

  7. Train, bus via Farragut

    1. Take the train from HARPERS FERRY W VA MARC eb to SILVER SPRING MARC ebtrain train
    2. Take the bus from Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    19h 54m
    $227–347

  8. Train, bus via Charlie Haun WB Aft Washington PK

    1. Take the train from HARPERS FERRY W VA MARC eb to Washington Union Stationtrain train
    2. Take the bus from Washington Union Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    24h 17m
    $162–226

  9. Train, bus via Rockville

    1. Take the train from HARPERS FERRY W VA MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the bus from Bethesda to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    25h 21m
    $159–221

Ronald Reagan Washington National Airport (DCA) to Mcghee Tyson Airport (TYS) flights

Calendar66Weekly Planes
Duration3h 38mAverage Duration
Ticket$172Cheapest Price
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Questions & Answers

Map of how to get from Harpers Ferry to Knoxville.ExpandLaunch map view
  • Distance: 508.1 mi
  • Duration: 4h 57m

What companies run services between Harpers Ferry, WV, USA and Knoxville, TN, USA?

There is no direct connection from Harpers Ferry to Knoxville. However, you can take the train to ROCKVILLE MARC eb, walk to Rockville, Red Line Center Platform, take the subway to Farragut North, Red Line Center Platform, walk to Farragut West, Blue/Orange/Silver Line Track 2 Platform, take the subway to Ronald Reagan Washington National Airport, Yellow/Blue Line Track 2 Platform-Trains South Toward Alexandria, walk to Ronald Reagan Washington National Airport (DCA) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from HARPERS FERRY W VA MARC eb to Knoxville via Washington Union Station, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, NY, and Knoxville, TN in around 18h 38m.

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