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How to get fromHarpers Ferry to St. Louisby train, plane, bus, train (Amtrak), car, subway, or bus (Greyhound)

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There are 7 ways to get from Harpers Ferry to St. Louis by train, plane, bus, train (Amtrak), car, subway, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Ronald Reagan Washington National Airport, fly

    best
    1. Take the train from HARPERS FERRY W VA MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    5h 45m
    $148–462

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    21h 6m
    $126–207

  3. Train, bus

    1. Take the train from Harpers Ferry Amtrak to Pittsburgh Amtrak Stationtrain train Floridian
    2. Take the bus from Pittsburgh Intermodal Station to St Louis Bus Stationbus bus Greyhound US0421
    20h 27m
    $158–286

  4. Train (Amtrak)

    1. Take the train from Harpers Ferry Amtrak to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    22h 23m
    $259–581

  5. Drive  754.9 mi

    1. Drive from Harpers Ferry to St. Louiscar car 754.9 mi
    13h 31m
    $138–199

  6. Train, train to Baltimore-Washington International Airport, fly

    1. Take the train from HARPERS FERRY W VA MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    6h 29m
    $130–1,235

  7. Train, subway to Washington Dulles International Airport, fly

    1. Take the train from HARPERS FERRY W VA MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Lambert–St. Louis International Airport (STL)plane plane IAD - STL
    6h 30m
    $197–1,031

Harpers Ferry to St. Louis by train and bus

Calendar7Weekly Services
Duration20h 27mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Harpers Ferry to St. Louis.ExpandLaunch map view
  • Distance: 790.3 mi
  • Duration: 5h 45m

What companies run services between Harpers Ferry, WV, USA and St. Louis, MO, USA?

You can take a train from Harpers Ferry Amtrak to St. Louis via Chicago Union Station in around 22h 23m. Alternatively, you can take a train from HARPERS FERRY W VA MARC eb to St Louis Bus Station via POINT OF ROCKS MARC eb, Point of Rocks MARC Train Station, Frederick Bus Station, and Pittsburgh Intermodal Station in around 21h 6m.

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