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How to get fromHarrisburg to Chicagoby bus, plane, taxi, train, bus (Greyhound, Flixbus), or car

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There are 8 ways to get from Harrisburg to Chicago by bus, plane, taxi, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Memphis, fly to Chicago Midway International Airport

    best
    1. Take the bus from Marked Tree to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Chicago Midway International Airport (MDW)plane plane MEM - MDW
    5h 45m
    $141–516

  2. Drive 530.7 mi

    cheapest
    1. Drive from Harrisburg to Chicagocar car 530.7 mi
    8h 59m
    $97–140

  3. Taxi, bus, train

    1. Take the taxi from Harrisburg to Tornado Bus Co - West Memphistaxi taxi
    2. Take the bus from Tornado Bus Co - West Memphis to Anna - Shellbus bus
    3. Take the train from Carbondale to Chicago Union Stationtrain train
    10h 52m
    $339–595

  4. Bus

    1. Take the bus from Marked Tree to Memphis Bus Stationbus bus Greyhound US1150s
    2. Take the bus from Memphis Bus Station to Chicago Bus Stationbus bus Greyhound US0125
    12h 1m
    $143–240

  5. Bus to Memphis, fly to Chicago O'Hare International Airport

    1. Take the bus from Marked Tree to Memphis Bus Stationbus bus
    2. Fly from Memphis (MEM) to Chicago O'Hare International Airport (ORD)plane plane MEM - ORD
    6h 16m
    $131–456

  6. Fly Jonesboro Municipal Airport to Chicago Midway International Airport

    1. Fly from Jonesboro Municipal Airport (JBR) to Chicago Midway International Airport (MDW)plane plane JBR - MDW
    5h 52m
    $116–395

  7. Taxi, bus to Bill And Hillary Clinton National Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from Harrisburg to Tornado Bus Co - West Memphistaxi taxi
    2. Take the bus from Tornado Bus Co - West Memphis to Shell Gas Station - Little Rock, ARbus bus
    3. Fly from Bill And Hillary Clinton National Airport (LIT) to Chicago O'Hare International Airport (ORD)plane plane LIT - ORD
    6h 55m
    $294–793

  8. Bus via Champaign

    1. Take the bus from Marked Tree to Memphis Bus Stationbus bus
    2. Take the bus from Memphis Bus Station to Champaign Intermodal Trans Ctrbus bus
    3. Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus bus
    14h 16m
    $183–270

Memphis (MEM) to Chicago Midway International Airport (MDW) flights

Calendar14Weekly Planes
Duration1h 35mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg to Chicago.ExpandLaunch map view
  • Distance: 559.8 mi
  • Duration: 5h 45m

What companies run services between Harrisburg, AR, USA and Chicago, IL, USA?

You can take a vehicle from Harrisburg to Chicago Bus Station via Marked Tree and Memphis Bus Station in around 12h 1m. Alternatively, Southern Airways Express and Southwest Airlines fly from Jonesboro Municipal Airport (JBR) to Chicago Midway International Airport (MDW) twice daily.

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