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How to get fromHarrisburg to Clevelandby bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), or train

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There are 6 ways to get from Harrisburg to Cleveland by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via State College Airport (SCE)

    best
    1. Take the bus from Harrisburg Bus Station to State College Regional Airportbus bus
    2. Take the bus from State College Regional Airport to Robert K Pfaff Transit Center - Akronbus bus
    3. Take the bus from Robert K Pfaff Transit Center - Akron to Cleveland, OHbus bus
    8h 50m
    $47–113

  2. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train Pennsylvanian
    2. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train Floridian
    9h 23m
    $115–249

  3. Drive 324.8 mi

    1. Drive from Harrisburg to Clevelandcar car 324.8 mi
    5h 37m
    $60–86

  4. Fly from Harrisburg International Airport

    1. Fly from Harrisburg International Airport (MDT) to Cleveland-Hopkins International Airport (CLE)plane plane MDT - CLE
    5h 27m
    $74–455

  5. Bus (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Cleveland Bus Stationbus bus Greyhound US0420
    9h 21m
    $54–99

  6. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Cleveland-Hopkins International Airport (CLE)plane plane PHL - CLE
    5h 41m
    $207–492

Harrisburg to Cleveland by bus

Calendar6Weekly Buses
Duration8h 50mAverage Duration
Ticket$47Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg to Cleveland.ExpandLaunch map view
  • Distance: 348 mi
  • Duration: 8h 50m

What companies run services between Harrisburg, Dauphin County, PA, USA and Cleveland, OH, USA?

You can take a bus from Harrisburg Bus Station to Cleveland, OH via State College Regional Airport and Robert K Pfaff Transit Center - Akron in around 8h 50m. Alternatively, you can take a train from Harrisburg to Cleveland Amtrak via Pittsburgh Amtrak Station in around 9h 23m.

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