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How to get fromHarrisburg to Detroitby plane, bus (Greyhound), train, bus, or car

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There are 5 ways to get from Harrisburg to Detroit by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Detroit (DTW)plane plane MDT - DTW
    4h 23m
    $68–434

  2. Bus (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Detroit Bus Stationbus bus Greyhound US0420
    13h 5m
    $75–150

  3. Train, bus

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Toledotrain train
    3. Take the bus from Toledo Bus Stop to Detroit Bus Stationbus bus
    13h 43m
    $155–357

  4. Drive 482.2 mi

    1. Drive from Harrisburg to Detroitcar car 482.2 mi
    7h 57m
    $88–128

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Detroit (DTW)plane plane PHL - DTW
    6h 25m
    $146–481

Harrisburg to Detroit by bus (Greyhound)

Calendar7Weekly Buses
Duration13h 5mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg to Detroit.ExpandLaunch map view
  • Distance: 401.7 mi
  • Duration: 4h 23m

What companies run services between Harrisburg, Dauphin County, PA, USA and Detroit, MI, USA?

Delta, United Airlines, and American Airlines fly from Harrisburg International Airport (MDT) to Detroit (DTW) every 4 hours. Alternatively, Greyhound USA operates a bus from Harrisburg Bus Station to Detroit Bus Station once daily. Tickets cost $75–150 and the journey takes 13h 5m.

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