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How to get fromHarrisburg to Florida Keysby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 5 ways to get from Harrisburg to Florida Keys by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Key West International Airport (EYW)plane plane MDT - EYW
    9h 6m
    $158–476

  2. Bus

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Miamibus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    32h 34m
    $209–361

  3. Train, bus

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    35h 46m
    $460–984

  4. Drive 1,302.7 mi

    1. Drive from Harrisburg to Florida Keyscar car 1,302.7 mi
    22h 34m
    $238–344

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)plane plane PHL - EYW
    9h 25m
    $211–713

Harrisburg to Florida Keys by bus, taxi, and foot

Calendar4Weekly Services
Duration32h 34mAverage Duration
Ticket$209Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg to Florida Keys.ExpandLaunch map view
  • Distance: 1,149.3 mi
  • Duration: 9h 6m

What companies run services between Harrisburg, Dauphin County, PA, USA and Florida Keys, FL, USA?

Delta, American Airlines, and United Airlines fly from Harrisburg International Airport (MDT) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Harrisburg Bus Station to Florida Keys via Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 32h 34m.

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