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How to get fromHarrisburg to Indianaby plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Flixbus)

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There are 6 ways to get from Harrisburg to Indiana by plane, train, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport, train

    best
    1. Fly from Harrisburg International Airport (MDT) to Chicago O'Hare International Airport (ORD)plane plane MDT - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 39m
    $65–326

  2. Bus

    1. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    13h 20m
    $80–160

  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    24h 24m
    $291–616

  4. Drive 538.9 mi

    1. Drive from Harrisburg to Indianapoliscar car 538.9 mi
    9h 23m
    $99–143

  5. Bus to Penn State University Park Airport, fly, train

    1. Take the bus from Harrisburg Bus Station to State College Regional Airportbus bus
    2. Fly from Penn State University Park Airport (SCE) to Chicago O'Hare International Airport (ORD)plane plane SCE - ORD
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 43m
    $73–336

  6. Bus via Indianapolis (Flixbus)

    1. Take the bus from Harrisburg Bus Station to Indianapolisbus bus FlixBus N2642 / ...
    13h 26m
    $85–152

Harrisburg to Indiana by bus

Calendar23Weekly Buses
Duration13h 20mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg to Indiana.ExpandLaunch map view
  • Distance: 650.1 mi
  • Duration: 5h 39m

What companies run services between Harrisburg, Dauphin County, PA, USA and Indiana, USA?

Greyhound USA operates a bus from Harrisburg Bus Station to Indianapolis Union Station twice daily. Tickets cost $80–160 and the journey takes 13h 20m. Flixbus USA also services this route once daily. Alternatively, you can take a train from Harrisburg to Indianapolis via 30th Street Station in around 24h 24m.

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