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How to get fromHarrisburg, Pa to Buffaloby plane, bus, train (Amtrak), car, or train

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There are 5 ways to get from Harrisburg, Pa to Buffalo by plane, bus, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Buffalo Niagara International Airport (BUF)plane plane MDT - BUF
    5h 51m
    $182–1,131

  2. Drive 280.8 mi

    cheapest
    1. Drive from Harrisburg, Pa to Buffalocar car 280.8 mi
    5h 32m
    $52–74

  3. Bus

    1. Take the bus from Harrisburg, Pa to Dubois, Pabus bus 731
    2. Take the bus from DuBois to Buffalobus bus Fab510 / ...
    10h 25m
    $57–197

  4. Train (Amtrak)

    1. Take the train from Harrisburg to Ny Moynihan Train Hall At Penn Stationtrain train Keystone Service / ...
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    13h 4m
    $203–416

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    5h 47m
    $147–799

Harrisburg, Pa to Buffalo by bus

Calendar1Weekly Buses
Duration10h 25mAverage Duration
Ticket$57Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to Buffalo.ExpandLaunch map view
  • Distance: 238.3 mi
  • Duration: 5h 51m

What companies run services between Harrisburg, Pa, PA, USA and Buffalo, NY, USA?

United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Harrisburg, Pa to Buffalo via DuBois in around 10h 25m.

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