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How to get fromHarrisburg, Pa to Charlestonby plane, train (Amtrak), car, train, or bus

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There are 5 ways to get from Harrisburg, Pa to Charleston by plane, train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Harrisburg International Airport to Charleston International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Charleston International Airport (CHS)plane plane MDT - CHS
    6h 48m
    $143–804

  2. Drive 609.9 mi

    cheapest
    1. Drive from Harrisburg, Pa to Charlestoncar car 609.9 mi
    11h 35m
    $112–161

  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    15h 30m
    $262–527

  4. Train to Philadelphia International Airport, fly to Charleston International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Charleston International Airport (CHS)plane plane PHL - CHS
    6h 55m
    $367–972

  5. Fly Harrisburg International Airport to Myrtle Beach, bus

    1. Fly from Harrisburg International Airport (MDT) to Myrtle Beach (MYR)plane plane MDT - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    8h 17m
    $130–698

Harrisburg International Airport (MDT) to Charleston International Airport (CHS) flights

Calendar121Weekly Planes
Duration4h 55mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to Charleston.ExpandLaunch map view
  • Distance: 560.5 mi
  • Duration: 6h 48m

What companies run services between Harrisburg, Pa, PA, USA and Charleston, SC, USA?

United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to Charleston International Airport (CHS) hourly. Alternatively, you can take a train from Harrisburg to Charleston via 30th Street Station and Charleston Amtrak Station in around 15h 30m.

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