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How to get fromHarrisburg, Pa to Detroitby plane, bus (Greyhound), train, bus, or car

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There are 5 ways to get from Harrisburg, Pa to Detroit by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Detroit (DTW)plane plane MDT - DTW
    4h 24m
    $143–854

  2. Bus

    cheapest
    1. Take the bus from Harrisburg Bus Station to Detroit Bus Stationbus bus Greyhound US0420
    12h 50m
    $80–160

  3. Train, bus

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Toledotrain train
    3. Take the bus from Toledo to Detroitbus bus
    13h 38m
    $160–359

  4. Drive 481.6 mi

    1. Drive from Harrisburg, Pa to Detroitcar car 481.6 mi
    7h 58m
    $88–127

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Detroit (DTW)plane plane PHL - DTW
    6h 25m
    $168–531

Harrisburg, Pa to Detroit by bus

Calendar14Weekly Buses
Duration12h 50mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to Detroit.ExpandLaunch map view
  • Distance: 401.9 mi
  • Duration: 4h 24m

What companies run services between Harrisburg, Pa, PA, USA and Detroit, MI, USA?

Delta, United Airlines, and American Airlines fly from Harrisburg International Airport (MDT) to Detroit (DTW) every 4 hours. Alternatively, Jefferson Lines operates a bus from Harrisburg Bus Station to Detroit Bus Station once daily. Tickets cost $110–160 and the journey takes 12h 50m. Greyhound USA also services this route once daily.

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