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How to get fromHarrisburg, Pa to Duke Universityby bus (Greyhound, Flixbus), bus, train, car, plane, bus (Greyhound), or train (Amtrak)

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There are 8 ways to get from Harrisburg, Pa to Duke University by bus (Greyhound, Flixbus), bus, train, car, plane, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    10h 1m
    $67–111

  2. Bus via Washington

    cheapest
    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the bus from Washington, DC - 2305 Pennsylvania Ave to Durham, NC - 3446 Hillsborough Rdbus bus New York
    10h 2m
    $52–92

  3. Bus, train

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the train from Washington Union Station to Durham Amtrak Stationtrain train Carolinian
    11h 6m
    $202–311

  4. Drive  369.3 mi

    1. Drive from Harrisburg, Pa to Duke Universitycar car 369.3 mi
    6h 44m
    $64–92

  5. Fly Harrisburg International Airport to Raleigh-Durham International Airport

    1. Fly from Harrisburg International Airport (MDT) to Raleigh-Durham International Airport (RDU)plane plane MDT - RDU
    6h 51m
    $78–479

  6. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Durham Amtrak Stationtrain train
    12h 22m
    $269–1,019

  7. Train to Philadelphia International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    6h 57m
    $140–267

  8. Fly Harrisburg International Airport to Charlotte Douglas International Airport, train

    1. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    8h 22m
    $173–691

Harrisburg, Pa to Duke University by bus and foot

Calendar4Weekly Services
Duration10h 1mAverage Duration
Ticket$67Cheapest Price
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Comparing Your Travel Options

Map of how to get from Harrisburg, Pa to Duke University.ExpandLaunch map view
  • Distance: 401.3 mi
  • Duration: 10h 1m

What companies run services between Harrisburg, Pa, PA, USA and Duke University, NC, USA?

You can take a bus from Harrisburg Bus Station to Duke University via Washington Union Station, Durham, Durham Station, and Flowers Dr at Duke Gardens in around 10h 1m. Alternatively, United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to Raleigh-Durham International Airport (RDU) every 2 hours.

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Need to know: Greyhound

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