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How to get fromHarrisburg, Pa to Duke Universityby bus (Greyhound, Flixbus), bus, train, car, plane, bus (Greyhound), or train (Amtrak)

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There are 7 ways to get from Harrisburg, Pa to Duke University by bus (Greyhound, Flixbus), bus, train, car, plane, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the bus from Washington Union Station to Durhambus bus FlixBus N2471 / ...
    9h 48m
    $59–115

  2. Bus via Washington

    cheapest
    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the bus from Washington, DC - 2305 Pennsylvania Ave to Durham, NC - 3446 Hillsborough Rdbus bus New York
    10h 17m
    $46–93

  3. Bus, train

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus Greyhound US0430
    2. Take the train from Washington Union Station to Durham Amtrak Stationtrain train Carolinian
    11h 41m
    $119–255

  4. Drive 369.3 mi

    1. Drive from Harrisburg, Pa to Duke Universitycar car 369.3 mi
    6h 43m
    $68–98

  5. Fly from Harrisburg International Airport

    1. Fly from Harrisburg International Airport (MDT) to Raleigh-Durham International Airport (RDU)plane plane MDT - RDU
    6h 49m
    $118–759

  6. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Durham Amtrak Stationtrain train
    12h 22m
    $166–940

  7. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    6h 56m
    $113–457

Harrisburg, Pa to Duke University by bus and foot

Calendar14Weekly Services
Duration9h 48mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to Duke University.ExpandLaunch map view
  • Distance: 376.1 mi
  • Duration: 9h 48m

What companies run services between Harrisburg, Pa, PA, USA and Duke University, NC, USA?

You can take a bus from Harrisburg Bus Station to Duke University via Washington Union Station, Durham, Durham Station, and Flowers Dr at Duke Gardens in around 9h 48m. Alternatively, United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to Raleigh-Durham International Airport (RDU) hourly.

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