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How to get fromHarrisburg, Pa to Iowaby plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

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There are 8 ways to get from Harrisburg, Pa to Iowa by plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Harrisburg International Airport to The Eastern Iowa Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to The Eastern Iowa Airport (CID)plane plane MDT - CID
    6h 3m
    $121–472

  2. Fly Harrisburg International Airport to Quad City International Airport

    cheapest
    1. Fly from Harrisburg International Airport (MDT) to Quad City International Airport (MLI)plane plane MDT - MLI
    7h 17m
    $78–414

  3. Train, bus

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    23h 59m
    $242–515

  4. Bus

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    24h 5m
    $174–268

  5. Drive  971.9 mi

    1. Drive from Harrisburg, Pa to Des Moinescar car 971.9 mi
    16h 3m
    $178–257

  6. Train to Philadelphia International Airport, fly to Des Moines

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    6h 23m
    $166–735

  7. Bus via Indianapolis (Greyhound)

    1. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    24h 20m
    $166–268

  8. Train, bus via Galesburg

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    25h 51m
    $262–580

Harrisburg International Airport (MDT) to The Eastern Iowa Airport (CID) flights

Calendar70Weekly Planes
Duration5h 49mAverage Duration
Ticket$80Cheapest Price
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Comparing Your Travel Options

Map of how to get from Harrisburg, Pa to Iowa.ExpandLaunch map view
  • Distance: 807.3 mi
  • Duration: 6h 3m

What companies run services between Harrisburg, Pa, PA, USA and Iowa, USA?

United Airlines, American Airlines, and Delta fly from Harrisburg International Airport (MDT) to The Eastern Iowa Airport (CID) every 3 hours. Alternatively, you can take a bus from Harrisburg Bus Station to Des Moines via Chicago Bus Station and Des Moines in around 24h 5m.

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