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How to get fromHarrisburg, Pa to Key Westby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 5 ways to get from Harrisburg, Pa to Key West by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Key West International Airport (EYW)plane plane MDT - EYW
    6h 28m
    $92–405

  2. Bus

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    32h 11m
    $200–317

  3. Train, bus

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to Hollywood Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    36h 54m
    $381–959

  4. Drive  1,317.5 mi

    1. Drive from Harrisburg, Pa to Key Westcar car 1,317.5 mi
    22h 58m
    $241–348

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Key West International Airport (EYW)plane plane PHL - EYW
    6h 49m
    $139–581

Harrisburg, Pa to Key West by bus and foot

Calendar4Weekly Services
Duration32h 11mAverage Duration
Ticket$200Cheapest Price
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Comparing Your Travel Options

Map of how to get from Harrisburg, Pa to Key West.ExpandLaunch map view
  • Distance: 1,130.3 mi
  • Duration: 6h 28m

What companies run services between Harrisburg, Pa, PA, USA and Key West, FL, USA?

American Airlines, Delta, and two other airlines fly from Harrisburg International Airport (MDT) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Harrisburg Bus Station to N Roosevelt & 3rd Street via Washington Union Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 32h 11m.

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