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How to get fromHarrisburg, Pa to Milwaukeeby plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, train, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Harrisburg, Pa to Milwaukee by plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Harrisburg International Airport to General Mitchell International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to General Mitchell International Airport (MKE)plane plane MDT - MKE
    5h 58m
    $99–555

  2. Fly Harrisburg International Airport to Chicago O'Hare International Airport, bus

    cheapest
    1. Fly from Harrisburg International Airport (MDT) to Chicago O'Hare International Airport (ORD)plane plane MDT - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    6h 14m
    $67–319

  3. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    18h 44m
    $439–691

  4. Bus

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150
    19h 10m
    $139–209

  5. Drive  744.1 mi

    1. Drive from Harrisburg, Pa to Milwaukeecar car 744.1 mi
    12h 31m
    $128–184

  6. Train to Philadelphia International Airport, fly to General Mitchell International Airport

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to General Mitchell International Airport (MKE)plane plane PHL - MKE
    6h 30m
    $441–943

  7. Bus via Detroit

    1. Take the bus from Harrisburg Bus Station to Detroit Bus Stationbus bus Greyhound US0420
    2. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus FlixBus 2550
    21h 45m
    $153–226

Harrisburg, Pa to Milwaukee by train (Amtrak)

Calendar7Weekly Trains
Duration18h 44mAverage Duration
Ticket$439Cheapest Price
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Comparing Your Travel Options

Map of how to get from Harrisburg, Pa to Milwaukee.ExpandLaunch map view
  • Distance: 622.4 mi
  • Duration: 5h 58m

What companies run services between Harrisburg, Pa, PA, USA and Milwaukee, WI, USA?

Delta, United Airlines, and American Airlines fly from Harrisburg International Airport (MDT) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a train from Harrisburg to Milwaukee via Pittsburgh Amtrak Station and Chicago Union Station in around 18h 44m.

Airlines
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