Rome2Rio

How to get fromHarrisburg, Pa to Missouriby plane, bus (Greyhound), train (Amtrak), car, train, or bus

Find Transport to Missouri

See all options

There are 6 ways to get from Harrisburg, Pa to Missouri by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to Lambert–St. Louis International Airport (STL)plane plane MDT - STL
    6h 26m
    $244–1,205

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    23h 5m
    $158–308

  3. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    24h 50m
    $370–771

  4. Drive 1,019.9 mi

    1. Drive from Harrisburg, Pa to Kansas Citycar car 1,019.9 mi
    17h 25m
    $187–269

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    6h 21m
    $189–873

  6. Bus, train

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus FlixBus N2640 / ...
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    25h 14m
    $269–503

Harrisburg, Pa to Missouri by bus (Greyhound)

Calendar14Weekly Buses
Duration23h 5mAverage Duration
Ticket$158Cheapest Price
See schedules

Questions & Answers

Map of how to get from Harrisburg, Pa to Missouri.ExpandLaunch map view
  • Distance: 755.3 mi
  • Duration: 6h 26m

What companies run services between Harrisburg, Pa, PA, USA and Missouri, USA?

Delta, United Airlines, and American Airlines fly from Harrisburg International Airport (MDT) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Harrisburg Bus Station to Kansas City Bus Station via St Louis Bus Station in around 23h 5m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers