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How to get fromHarrisburg, Pa to San Antonioby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus (Flixbus)

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There are 6 ways to get from Harrisburg, Pa to San Antonio by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to San Antonio International Airport (SAT)plane plane MDT - SAT
    7h 53m
    $163–754

  2. Bus

    1. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus
    2. Take the bus from Baltimore Downtown Bus Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Dallas Bus Stationbus bus
    4. Take the bus from Dallas Bus Station to San Antonio Bus Stationbus bus
    39h 30m
    $252–502

  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to San Antonio Stationtrain train
    2d 1h
    $602–1,297

  4. Drive 1,645.5 mi

    1. Drive from Harrisburg, Pa to San Antoniocar car 1,645.5 mi
    26h 39m
    $301–434

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to San Antonio International Airport (SAT)plane plane PHL - SAT
    8h 5m
    $217–922

  6. Bus via Chicago

    1. Take the bus from Harrisburg Bus Station to Chicagobus bus FlixBus N2640
    2. Take the bus from Chicago to Tornado Bus Co - San Antoniobus bus Chicago
    42h 32m
    $311–548

Harrisburg, Pa to San Antonio by bus

Calendar7Weekly Buses
Duration39h 30mAverage Duration
Ticket$252Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to San Antonio.ExpandLaunch map view
  • Distance: 1,447.3 mi
  • Duration: 7h 53m

What companies run services between Harrisburg, Pa, PA, USA and San Antonio, TX, USA?

American Airlines, United Airlines, and Delta fly from Harrisburg International Airport (MDT) to San Antonio International Airport (SAT) hourly. Alternatively, you can take a bus from Harrisburg Bus Station to San Antonio Bus Station via Baltimore Downtown Bus Station, Nashville Bus Station, and Dallas Bus Station in around 39h 30m.

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