Rome2Rio

How to get fromHarrisburg, Pa to San Diegoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Find Transport to San Diego

See all options

There are 7 ways to get from Harrisburg, Pa to San Diego by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to San Diego International Airport (SAN)plane plane MDT - SAN
    8h 38m
    $181–752

  2. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    4. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 15h
    $907–2,050

  3. Bus

    1. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to San Diegobus bus
    2d 16h
    $420–812

  4. Drive 2,577.3 mi

    1. Drive from Harrisburg, Pa to San Diegocar car 2,577.3 mi
    42h 31m
    $471–680

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to San Diego International Airport (SAN)plane plane PHL - SAN
    9h 3m
    $195–530

  6. Train, train to Baltimore-Washington International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to San Diego International Airport (SAN)plane plane BWI - SAN
    9h 58m
    $406–1,367

  7. Bus, train

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to San Diegotrain train
    2d 15h
    $801–1,767

Harrisburg, Pa to San Diego by train (Amtrak)

Calendar7Weekly Trains
Duration2d 15hAverage Duration
Ticket$907Cheapest Price
See schedules

Questions & Answers

Map of how to get from Harrisburg, Pa to San Diego.ExpandLaunch map view
  • Distance: 2,294.3 mi
  • Duration: 8h 38m

What companies run services between Harrisburg, Pa, PA, USA and San Diego, CA, USA?

United Airlines, Delta, and American Airlines fly from Harrisburg International Airport (MDT) to San Diego International Airport (SAN) hourly. Alternatively, you can take a train from Harrisburg to San Diego via Pittsburgh Amtrak Station, Chicago Union Station, and Fullerton Amtrak Station in around 2d 15h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers