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How to get fromHarrisburg, Pa to San Franciscoby plane, bus (Greyhound), train (Amtrak), car, train, or bus

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There are 7 ways to get from Harrisburg, Pa to San Francisco by plane, bus (Greyhound), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport

    best
    1. Fly from Harrisburg International Airport (MDT) to San Francisco International Airport (SFO)plane plane MDT - SFO
    9h 27m
    $140–564

  2. Bus (Greyhound)

    1. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus bus
    2d 20h
    $455–897

  3. Train (Amtrak)

    1. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Richmondtrain train
    2d 22h
    $919–2,076

  4. Drive 2,767.4 mi

    1. Drive from Harrisburg, Pa to San Franciscocar car 2,767.4 mi
    43h 25m
    $505–730

  5. Train to Philadelphia International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to San Francisco International Airport (SFO)plane plane PHL - SFO
    9h 55m
    $223–681

  6. Train, train to Baltimore-Washington International Airport, fly

    1. Take the train from Harrisburg to 30th Street Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to San Francisco International Airport (SFO)plane plane BWI - SFO
    10h 52m
    $214–1,278

  7. Bus, train

    1. Take the bus from Harrisburg Bus Station to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Richmondtrain train
    2d 23h
    $823–1,799

Harrisburg, Pa to San Francisco by bus (Greyhound)

Calendar7Weekly Buses
Duration2d 20hAverage Duration
Ticket$455Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to San Francisco.ExpandLaunch map view
  • Distance: 2,456.2 mi
  • Duration: 9h 27m

What companies run services between Harrisburg, Pa, PA, USA and San Francisco, CA, USA?

Delta, United Airlines, and American Airlines fly from Harrisburg International Airport (MDT) to San Francisco International Airport (SFO) hourly. Alternatively, you can take a bus from Harrisburg Bus Station to San Francisco Bus Station via St Louis Bus Station and Los Angeles Union Station in around 2d 20h.

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Need to know: Greyhound

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