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How to get fromHarrisburg, Pa to South Carolinaby plane, taxi, train (Amtrak), car, bus, or train

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There are 5 ways to get from Harrisburg, Pa to South Carolina by plane, taxi, train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Harrisburg International Airport, taxi

    best
    1. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    3h 40m
    $161–592

  2. Drive 609.9 mi

    cheapest
    1. Drive from Harrisburg, Pa to Charlestoncar car 609.9 mi
    11h 35m
    $112–161

  3. Train (Amtrak)

    1. Take the train from Harrisburg to 30th Street Stationtrain train Keystone Service / ...
    2. Take the train from 30th Street Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    15h 30m
    $251–526

  4. Bus to Penn State University Park Airport, fly, taxi

    1. Take the bus from Harrisburg Bus Station to State College Regional Airportbus bus
    2. Fly from Penn State University Park Airport (SCE) to Charlotte Douglas International Airport (CLT)plane plane SCE - CLT
    3. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    4h 56m
    $174–613

  5. Bus, train, taxi

    1. Take the bus from Harrisburg Bus Station to Washington Union Stationbus bus
    2. Take the train from Washington Union Station to Savannah Stationtrain train
    3. Take the taxi from Savannah Station to Bluffton Transfer Centertaxi taxi
    4. Take the bus from Bluffton Transfer Center to Walmartbus bus 320
    5. Take the taxi from Walmart to Dorchester Village Shopping Center Park & Ridetaxi taxi
    22h

Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT) flights

Calendar81Weekly Planes
Duration2h 41mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Harrisburg, Pa to South Carolina.ExpandLaunch map view
  • Distance: 450.1 mi
  • Duration: 3h 40m

What companies run services between Harrisburg, Pa, PA, USA and South Carolina, USA?

You can take a train from Harrisburg to Charleston via 30th Street Station and Charleston Amtrak Station in around 15h 30m.

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